Recombinant human basic-fibroblastic growth factor: different medical dressings for clinical application in wound healing. |
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Authors: | G Finetti M Farina |
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Institution: | R&D Galenical Department of Farmitalia Carlo Erba Malano, Italy. |
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Abstract: | Recombinant human basic-Fibroblastic Growth Factor (rhb-FGF) is a basic single-chain protein showing high activity as mitogenetic and angiogenetic agent. The application of rhb-FGF in wound healing as stimulator of the tissue repair process is strictly connected with the covering of the wound by means of a proper dressing. A wide number of synthetic occlusive or non-occlusive wound dressings has been developed. Owing to the delicate proteic structure of rhb-FGF, and generally of all the Growth Factors, compatibility with the dressings has to be every time tested, to avoid its inactivation and consequent loss of tissue repair properties. |
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