血清肌钙蛋白I对儿童病毒性心肌炎的诊断价值

目的了解心肌特异性肌钙蛋白Ⅰ（ｃＴｎＩ）对病毒性心肌炎的诊断价值。方法用双抗ＥＬＩＳＡ法动态测定４６例病毒性心肌炎患的血清ｃＴｎＩ，同时检测肌酸激酶同功酶（ＣＫ－ＭＢ）。结果４６例患ｃＴｎＩ的阳性率为８０．４％，ＣＫ－ＭＢ的阳性率为４５．７％（Ｐ〈０．０５）。病程１５天ｃＴｎＩ的检出率为８０．４％，而ＣＫ－ＭＢ的检出率为２１．３％（Ｐ〈０．０１）。病程６０天ｃＴｎＩ的检出率为２４．４％，而ＣＫ

Diagnostic value of serum troponin I in children with viral myocarditis

Objective To evaluate the diagnostic value of cardiac troponin I(cTnI) in myocardial injury of viral myocarditis(VMC).Methods Serum levels of cTnI was assayed with a double monoclonal ELISA.Concentration of isoenyme of creatine kinase(CK-MB) was measured at the same time.Results In 46 patients with VMC,the positive detection rate of cTnI was 80 4%,and that of CK-MB was only 45 7%( P <0 05).At the fifteenth day,the positive detection rate of cTnI was 80 4%,but that of CK-MB was only 21 3%( P <0 01).At the sixtieth day,the positive detection rate of cTnI was 24 4% and that of CK-MB was normal.Conclusion The sensitivity and specificity of the serum cTnI to diagonse VMC are excellent,and the assay window time of cTnI is also longer than that of CK-MB.The assay of cTnI might become a good index in the early diagonsis of VMC and the determin ation of its progress.