| 心肌血流储备分数在冠心病介入治疗中的应用 |
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| 引用本文： | 汤成春,马根山,冯毅,陈忠,鞠成伟,章晓国,王润民,陈琴芬,鞠翔,谢学玲.心肌血流储备分数在冠心病介入治疗中的应用[J].江苏医药,2011,37(8). |
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| 作者姓名： | 汤成春 马根山 冯毅 陈忠 鞠成伟 章晓国 王润民 陈琴芬 鞠翔 谢学玲 |
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| 作者单位： | 东南大学附属中大医院心脏病科,南京市,210009 |
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| 摘 要： | 目的探讨心肌血流储备分数(FFR)在冠脉介入治疗(PCI)术中的应用价值。方法冠状动脉造影(CAG)明确冠脉病变面积狭窄70%以上患者32例(66处病变)。对照组16例患者32处病变常规行PCI植入药物涂层支架(DES);实验组16例患者34处病变均行FFR测定,仅在FFR值≤0.80的病变植入DES,术后FFR值仍≤0.80患者给予支架内后扩张。比较两组患者手术时间、造影剂用量、植入支架数目;出院1个月后心绞痛症状、主要心脏不良事件(MACE)发生率。结果实验组支架植入数量、造影剂用量明显少于对照组(1.7±0.9 vs.2.2±0.8)个(、186±98)mlvs.(256±116)ml](P<0.01);两组手术时间和出院1个月后不良事件发生率无显著性差异。结论测定冠脉病变FFR值来指导PCI术,能显著减少造影剂用量及支架植入数量,评价支架贴壁效果,短期并不增加心绞痛发作和MACE发生率。
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| 关 键 词： | 冠心病 心肌血流储备分数 经皮冠状动脉介入治疗 |
Application of fractional flow reserve for guiding percutaneous coronary intervention |
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| TANG Chengchun,MA Genshan,FENG Yi,et al..Application of fractional flow reserve for guiding percutaneous coronary intervention[J].Jiangsu Medical Journal,2011,37(8). |
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| Authors: | TANG Chengchun MA Genshan FENG Yi |
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| Institution: | TANG Chengchun,MA Genshan,FENG Yi,et al.Department of Cardiology,Affiliated Zhongda Hospital,Southeast University,Nanjing 210009,CHINA |
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| Abstract: | Objective To study the value of application of fractional flow reserve(FFR) for guiding percutaneous coronary intervention(PCI) in patients with coronary artery disease(CAD).Methods Thirty-two CAD patients with 66 lesions were divided into two groups with 16 cases each.The patients in group A(34 lesions) underwent FFR measurements in each diseased coronary artery,and drug-eluting stents(DES) were placed in indicated lesions only if the FFR was 0.08 or less.The patients in group B(32 lesions) underwent DES i... |
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| Keywords: | Coronary artery disease Fractional flow resever Percutaneous coronary intervention |
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