Emerging innovations in cold plasma therapy against cancer: A paradigm shift |
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Affiliation: | 1. R&D Healthcare Division, Emami, 13 BT Road, Belgharia, Kolkata 700056, India;2. Department of Pharmacy, Birla Institute of Technology and Science, Pilani, Pilani Campus, Rajasthan 333031, India;3. Council of Scientific and Industrial Research (CSIR)-Central Electronics Engineering Research Institute (CEERI), Pilani, Rajasthan 333031, India;4. School of Physics, Devi Ahilya Vishwavidyalaya, Indore, Madhya Pradesh 452001, India;5. RNA Structure and Design Section, RNA Biology Laboratory (RBL), Center for Cancer Research, National Cancer Institute – Frederick, Frederick, MD 21702, USA;6. Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India |
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Abstract: | Cancer is one of the major causes of mortality, accounting for ~ 9.5 million deaths globally in 2018. The spectrum of conventional treatment for cancer includes surgery, chemotherapy and radiotherapy. Recently, cold plasma therapy surfaced as a novel technique in the treatment of cancer. The FDA approval of the first trial for the use of cold atmospheric plasma (CAP) in cancer therapy in 2019 is evidence of this. This review highlights the mechanisms of action of CAP. Additionally, its applications in anticancer therapy have been reviewed. In summary, this article will introduce the readers to the exciting field of plasma oncology and help them understand the current status and prospects of plasma oncology. |
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Keywords: | Cold plasma Cold atmospheric plasma Cancer Plasma oncology Anticancer therapy |
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