板蓝根水提取液中的化学成分

目的研究板蓝根水提取液中的化学成分。方法板蓝根水提取液经D101大孔树脂吸附，不同浓度乙醇洗脱部分经硅胶柱色谱反复分离纯化，测定所得化合物的理化常数和波谱数据，鉴定其化学结构。结果从板蓝根水提取液中分离得到5个化合物，分别鉴定为：3-［2′-(5′-羟甲基)呋喃基］-1(2H)-异喹啉酮-7-O-β-D-葡糖苷(I)、落叶松树脂醇-4，4′-二-O-β-D-吡喃葡糖苷(II)、落叶松树脂醇-4-O-β-D-吡喃葡糖苷(III)、2-羟基-1，4-苯二甲酸(IV)、甘露醇(V)。结论化合物I为新化合物，化合物IV和V在板蓝根中首次分离得到。

Chemical constituents from water extract of Radix isatidis

AIM: To study the chemical constituents from water extract of Radix isatidis. (Isatis indigotica Fort. ). METHODS: The water extract was underwent absorption by D101 macroporous resin, the portion eluted by ethanol of different concentrations was isolated and purified on silica gel column repeatedly. The obtained compounds were identified and structurally elucidated by their physico-chemical properties and spectral analysis. RESULTS: Five compounds were isolated from water extract of Radix isatidis, and were partly identified separately: 3-2'-(5'-hydroxymethyl) furyl] -1 (2H) -isoquinolinone-7-O-beta-D-glucoside (I), lariciresinol-4,4'-di-O-beta-D-glucopyranoside (II), lariciresinol-4-O-beta-D-glucopyranoside (III), 2-hydroxy-1, 4-benzenedicarboxylic acid (IV), mannitol (V). CONCLUSION: Compound I is a new compound and compounds IV and V were isolated from the plant for the first time.