| 大叶香茶菜抗肿瘤成分的研究 |
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| 引用本文： | 程培元,许美娟,林永乐,石金城.大叶香茶菜抗肿瘤成分的研究[J].药学学报,1981,16(10):796-797. |
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| 作者姓名： | 程培元 许美娟 林永乐 石金城 |
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| 作者单位： | 南京药物研究所
(程培元，许美娟，林永乐)，南京药物研究所(石金城) |
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| 摘 要： | 大叶香茶菜Rabdosia macrophylla(Migo)C.Y.Wu et H.W.Li]系唇形科香茶菜属植物,其成分研究尚未见报道。为寻找抗癌活性成分,我们从中分得十一种成分,通过体外肝癌细胞培养、抑菌试验和动物瘤谱筛选,证明丙、己、庚、辛、11号等二萜具有抗癌和抑菌活性。根据物理常数及光谱分析证明丙、戊、己分别为冬凌草素即Oridonin、β
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| 收稿时间： | 1980-07-08 |
THE ANTITUMOR CONSTITUENTS OF RABDOSIA MACROPHYLLA |
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| Cheng Peiyuan,Xu Meijuan,Lin Yongle and Shi Jincheng.THE ANTITUMOR CONSTITUENTS OF RABDOSIA MACROPHYLLA[J].Acta Pharmaceutica Sinica,1981,16(10):796-797. |
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| Authors: | Cheng Peiyuan Xu Meijuan Lin Yongle and Shi Jincheng |
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| Abstract: | From the Chinese drug Rabdosia macrophylla eleven components were isolated. Several of them showed significant cytotoxicity on heptoma cells, anti-staphyloccocus aurea efficacy and tumor inhibitory activity against Ehrlich ascites carcinoma in mice. By means of spectral method combined with chemical analysis, three of the components were identified to be oridonin, β-sito-sterol and isodonal. In this paper, the isolation and identification of oridonin and isodonal were reported. |
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