| 草药牛筋果化学成分的研究 |
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| 引用本文： | 王玫馨,张敏生,朱元龙.草药牛筋果化学成分的研究[J].药学学报,1983,18(2):113-118. |
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| 作者姓名： | 王玫馨 张敏生 朱元龙 |
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| 作者单位： | 中山医学院化学教研室，中山医学院化学教研室，中国科学院上海药物研究所 广州，广州 |
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| 摘 要： | 从苦木科牛筋果属植物牛筋果(Harrisonia perforate (Blanco)Merr.)根中分得四种色原酮化合物,(1)异前胡色原酮-7-甲醚,(2)异前胡色原酮-5-甲氧基-7-甲醚。其余两种是新化合物命名为牛筋果色原酮甲、乙,其结构如Ⅲ,Ⅳ式所示。
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| 关 键 词： | 牛筋果 色原酮 牛筋果色原酮甲、乙 |
| 收稿时间： | 1981-11-30 |
STUDIES ON THE CHEMICAL CONSTITUENTS OF A CHINESE FOLK MEDICINE NIU-JINGUO (HARRISONIA PERFORATE BLANO MERR) |
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| WANG Mei-Xin,ZHANG Min-sheng and ZHU Yuan-long.STUDIES ON THE CHEMICAL CONSTITUENTS OF A CHINESE FOLK MEDICINE NIU-JINGUO (HARRISONIA PERFORATE BLANO MERR)[J].Acta Pharmaceutica Sinica,1983,18(2):113-118. |
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| Authors: | WANG Mei-Xin ZHANG Min-sheng and ZHU Yuan-long |
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| Abstract: | The root of a Chinese folk medicine, Niu-Jin-Guo. (Harrisonia perforate Blano Merr.) has been used for treatment of malaria. In order to exploite the active principles, we have studied the chromonic compounds of this plant.Four chromonic compounds have been obtained by silicagel column chromatography from the roots. According to their spectroscopic data (UV, IR, NMR, MS),preparation of derivatives, acid hydrolysis products and determination of physico-chemical constants, one of them was identified as heteropeucenin-7-methyl ether. Another one was identified as. heteropeucenin-5-methoxy-7-methyl ether.In addition, two other compounds were obtained Which were new chromones and named perforatin A and B. Their structures were established. as shown in formula Ⅲ and Ⅳ respectively.Bioactive test of these chromones is in progress. |
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| Keywords: | Harrisonia perforate Chromone Heteropeucenin-7-methyl ether Heteropeucenin-5-methoxy-7-methyl ether perforatin A B |
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