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鹅掌藤中三萜类化合物的分离与鉴定
引用本文:郭夫江,林绥,李援朝.鹅掌藤中三萜类化合物的分离与鉴定[J].中国药物化学杂志,2005,15(5):294-296.
作者姓名:郭夫江  林绥  李援朝
作者单位:1. 中国科学院,上海药物研究所,上海,201203
2. 福建省医学科学研究所,福建,福州,350001
基金项目:植物样品承福建中医学院车书容先生鉴定.
摘    要:目的研究五加科鹅掌柴属植物鹅掌藤(Schefflera arboricola)枝茎的化学成分.方法采用柱色谱分离,通过理化数据和光谱分析确定化合物的结构.结果从鹅掌藤乙酸乙酯提取物中分离得到7个三萜化合物,分别鉴定为羽扇醇(1)、桦木酸(2)、3-epi-betulinic acid(3)、齐墩果酸(4)、3-乙酰齐墩果酸(5)、mesembryanthemoidigenic acid(6)、quinatic acid(7).结论化合物1、5、6、7为首次从该属植物中分得.

关 键 词:药物化学  结构鉴定  柱色谱法  鹅掌藤  三萜化合物
文章编号:1005-0108(2005)05-0294-03
收稿时间:2005-05-18
修稿时间:2005-05-18

Isolation and identification of triterpenoids from Schefflera arboricola
GUO Fu-jiang,LIN Sui,LI Yuan-chao.Isolation and identification of triterpenoids from Schefflera arboricola[J].Chinese Journal of Medicinal Chemistry,2005,15(5):294-296.
Authors:GUO Fu-jiang  LIN Sui  LI Yuan-chao
Institution:1. Shanghai Institute of Materia Medica , Chinese Academy of Sciences, Shanghai 201203, China ; 2. Fujian Institute of Medical Sciences, Fuzhou 350001, China
Abstract:Aim To study the chemical constituents in the stem of Schefflera arboricola.Methods Seven compounds were isolated and purified by column chromatography.Their structures were identified by physicochemical properties and spectral analysis.Results Seven triterpenoids were isolated and identified as lupeol(1),betulinic acid(2),3-epi-betulinic acid(3),oleanolic acid(4),3-acetyloleanolic acid(5),mesembryanthemoidigenic acid(6),quinatic acid(7).Conclusion Compounds 1,5,6,7 are isolated from this genus for the first time.
Keywords:medicinal chemistry  structural identification  column chromatography  Schefflera arboricola  triterpenoids
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