| 蒙药巴特尔-7体外对胃癌细胞生长的影响 |
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| 引用本文： | 邓秀玲,刘淑萍,王栋.蒙药巴特尔-7体外对胃癌细胞生长的影响[J].中国实用医药,2011,6(27):60-62. |
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| 作者姓名： | 邓秀玲 刘淑萍 王栋 |
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| 作者单位： | 1. 内蒙古医学院生物化学与分子生物学教研室,呼和浩特,010059
2. 内蒙古自治区医院神经内科 |
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| 摘 要： | 目的观察蒙药巴特尔-7对体外培养的人胃癌MGC-803细胞生长的影响。方法 MGC-803细胞经不同浓度蒙药处理后,通过MTT比色法分析蒙药作用后细胞的增殖情况。在倒置光显微镜及荧光显微镜下,观察细胞形态的变化;应用琼脂糖凝胶电泳分析诱导凋亡作用。结果巴特尔-7能抑制MGC-803细胞的增殖,且抑制作用随药物浓度的增加而增加。光镜下见部分细胞呈现凋亡的形态改变,琼脂糖凝胶电泳未见明显的梯状带。结论巴特尔-7对胃癌MGC-803细胞生长具有明显的抑制作用。
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| 关 键 词： | 蒙药 胃癌细胞 凋亡 |
Effect of Inner Mongolia Drugs Bateer-7 on growth of human gastric cancer in vitro |
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| DENG Xiu-ling,LIU Shu-ping,WANG Dong.Effect of Inner Mongolia Drugs Bateer-7 on growth of human gastric cancer in vitro[J].China Practical Medical,2011,6(27):60-62. |
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| Authors: | DENG Xiu-ling LIU Shu-ping WANG Dong |
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| Institution: | DENG Xiu-ling,LIU Shu-ping,WANG Dong.Department of Biochemistry and Molecular Biology,Inner Mongolia Medical College,Hohhot 010059,China |
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| Abstract: | Objective To studay the effect of Inner Mongolia Drug Bateer-7 on growth of humand gastric cancer MGC-803 cell in vitro.Methods Bateer-7 in different dose were used to treat MGC-803 cell,then MTT assay was employed to examine the proliferation inhibitory effect of Mongolia Drug on MGC-803 cell.Morphologic changes were observed by reverse discrepancy and offluorescent light staining microscope.DNA electophoresis was uitilized to detect the apoptosis of MGC-803 cell induced by Bateer-7.Results MTT assay showe... |
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| Keywords: | Inner Mongolia Drugs Gastric cancer cell apoptosis |
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