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儿科住院患者抗菌药物使用调查
引用本文:程虹,吴东方.儿科住院患者抗菌药物使用调查[J].药物流行病学杂志,2014(12):737-740.
作者姓名:程虹  吴东方
作者单位:武汉大学中南医院药学部(武汉 430071);武汉大学中南医院药学部
基金项目:武汉大学中南医院管理基金项目(编号:2013B01)
摘    要:目的:调查儿科住院患者抗菌药物使用情况,促进儿科抗菌药物合理使用。方法:回顾性调查2013年1-12月所有儿科出院患者病历,统计抗菌药物使用各项指标,分析适应证是否合理。结果:1 352例儿科住院患者中,抗菌药物使用率为96.60%,细菌感染性疾病和真菌感染性疾病病例均使用了抗菌药物,病毒感染性疾病患者抗菌药物使用率为91.17%,非感染性疾病患者的抗菌药物使用率为79.31%。抗菌药物单用比例为62.33%。使用抗菌药物患者病原学检查百分率65.93%。抗菌药物使用强度为58.96,头孢菌素酶抑制药复合制剂使用强度为18.16,为各类抗菌药物中最高。结论:儿科住院患者抗菌药物使用率过高,特别是病毒性感染疾病和非感染性疾病无适应证使用抗菌药物,抗菌药物使用强度过高,是儿科住院患者抗菌药物使用存在的突出问题,也是未来抗菌药物管理中需要重视和改进的方面。

关 键 词:儿科  住院患者  抗菌药物  合理用药  药物利用

Survey of Antimicrobial Agents Use in Pediatric Inpatients
Cheng Hong and Wu Dongfang.Survey of Antimicrobial Agents Use in Pediatric Inpatients[J].Chinese Journal of Pharmacoepidemiology,2014(12):737-740.
Authors:Cheng Hong and Wu Dongfang
Institution:Zhongnan Hospital of Wuhan University, Wuhan 430071, China;Zhongnan Hospital of Wuhan University
Abstract:Objective:To promote rational use of antimicrobial agents in Pediatric inpatients. Methods:The use of antimicrobial agents of Pediatric inpatients who were discharged from the Pediatric Department from January to December was retrospective analyzed. Results:Among 1352 Pediatric inpatients, antimicrobial agents utilization rate was 96.6%. All patients with bacteria and fungal infectious diseases have used antibiotics. Antimicrobial agents utilization rate in patients with viral infectious diseases was 91.17%, antimicrobial agents in patients with non-infectious diseases was 79.31%. Utilization rate of monoantimicrobial agents was 62.33%. The percentage of etiology examination before use of antimicrobial agents was 65.93%. Antimicrobial drug use intensity was 58.96, eephalosporin/enzyme inhibitor use intensity was 18.16, the highest among all kinds of antibiotics. Conclusion: The level of antimicrobial agents utilization rate of Pediatric inpatients was too high, especially those patients with viral infections or non-infectious disease, who did not' t have any indica- tions for antimicrobial agents. Antimicrobial agents use intensity was high. Those problems existing in the use of antimicrobial agents need to take seriously and improve in the future.
Keywords:Pediatric  Inpatients  Antimicrobial agents  Rational drug use  Drug utilization
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