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注射用头孢他啶、头孢曲松钠与二羟丙茶碱注射液在4种输液中配伍后的稳定性
引用本文:翟晓波,顾斌,张楠森.注射用头孢他啶、头孢曲松钠与二羟丙茶碱注射液在4种输液中配伍后的稳定性[J].中国药师,2002,5(1):29-30.
作者姓名:翟晓波  顾斌  张楠森
作者单位:1. 上海市东方医院药剂科,200120
2. 上海市第六人民医院
摘    要:目的:考察室温下6h内注射用头孢他啶、头孢曲松纳与二羟丙茶碱注射液在4种输液中配伍后稳定性。方法:采用双波长分光光度法测定各配伍溶液中头孢他啶、头孢曲松钠的含量变化情况。结果:室温下注射用头孢他啶、头孢曲松钠单独与4种输液配伍后其RSD都在0.5%以下,相同条件下注射用头孢他啶、头孢曲松钠分别于二羟丙茶碱注射液配伍后在4种输液中的RSD与前者比较变化不大。结论:注射用头孢他啶、头孢曲松钠分别与二羟丙茶碱注射液配伍后在4种输液中6h内保持基本稳定。

关 键 词:头孢他啶  头孢曲松钠  二羟丙茶碱  配伍稳定性
修稿时间:2001年5月14日

Compatibility of Ceftazidime or Ceftriaxone Sodium with Diprophyliine in Four Kinds of Intravenous Transfusion
Zhai Xiaobo,Gu bing,Zhang Nansen.Compatibility of Ceftazidime or Ceftriaxone Sodium with Diprophyliine in Four Kinds of Intravenous Transfusion[J].China Pharmacist,2002,5(1):29-30.
Authors:Zhai Xiaobo  Gu bing  Zhang Nansen
Abstract:Objective: To explore the compatibility of cefazidime or ceftriaxone sodium with diprophylline in four kinds of transfusions at room temperature for 6 hours. Methods: The changes of contents of ceftazidime or ceftriaxone sodium in four kinds of transfusions by dual wavelength spectrophotometry. Results: The contents of ceftazidime or ceftriaxone sodium degraded less than 1 % and 0.5%, respectively within 6 hours after they were admixed alone with the four kinds of transfusions, while the contents of ceftazidime or ceftriaxone sodium did not change significantly 6 hours after thery were admixed with diprophylline and added in four kinds of transfusions, respectively. Conclusion:The contents, of which 6 hours after ceftazidime or ceftriaxone sodium are admixed with diprophylline and added in the four kinds of transfusions, respectively, may be kept the stability essentially.
Keywords:Ceftazidime  Ceftriaxone sodium  Diprophylline  Compatibility
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