丹香冠心注射液治疗新生儿高胆红素血症60例疗效观察

目的探讨丹香冠心注射液治疗新生儿高胆红素血症的临床疗效。方法将110例患儿随机分为治疗组(60例)和对照组(50例),两组均行常规治疗,治疗组加用丹香冠心注射液2～3mL/(kg.d)溶入10%GS50～100mL中静脉滴注,每日1次,连用5～7d。结果治疗组显效率、总有效率分别为76.7%、95.0%;对照组显效率、总有效率分别为54.0%、86.0%,两组比较有统计意义(P<0.01)。两组治疗前后血清总胆红素第1d下降值、日平均下降值、降至80μmol/L以下时间比较有统计意义(P<0.01或P<0.001)。结论丹香冠心注射液治疗新生儿高胆红素血症疗效明显,药源充足、价廉,值得推广。

Investigate the effect of Danxiang Guanxin injection on newborn with hyperbilirubinemia

ObjectiveTo investigate the effect of Danxiang Guanxin injection to treat the newborn with hyperbilirubinemia. Methods 110 patients were divided randomly into two groups. The treatment group (n=60) were treated by intravenous drip with Danxiang Guanxin injection. The control group (n=50) were on the same basic conditions as the treatment group, and observed the effect of reducing the serum total bilirubin. Results 76.7 % were shown to be improved significantly in the treatment group, 95.0 % were shown to be improved slightly. 54.0 % were shown to be improved significantly in the control group , 86.0 % were shown to be improved slightly. There was significant difference in the effects between the two groups(P<0.01).There was also significant difference in the degression of serum total bilirubin between the two groups(P<0.01).Conclusion This study clearly conforms that it is an effective method to treat newborn with hyperbilirubinemia with Danxiang Guanxin injection, and no adverse effect been observed.