间充质干细胞联合石墨烯支架培养治疗膝骨性关节炎的研究进展

膝骨性关节炎是困扰中老年人的疾病之一， 关节软骨损伤是其病理过程的核心， 围绕软骨损伤的病理研 究也越来越深入， 而现有的治疗方法尚不能从根本上逆转这一过程。近年来随着软骨组织工程技术的发展， 特别是 间充质干细胞的使用为解决这一困难提供了一条新的途径。同时， 石墨烯材料在医学领域的应用也逐渐成为热门， 利用石墨烯材料作为支架结构联合间充质干细胞， 以此寻求对软骨损伤修复的新方法。本文从膝软骨损伤的机制、 间充质干细胞对软骨的修复以及石墨烯支架材料的应用方面进行总结， 以期能开拓新的治疗思路。

Prospect of mesenchymal stem cells combined with graphene scaffold materials on knee osteoarthritis

Knee osteoarthritis is one of diseases that afflict the middle-aged and old people. Articular cartilage injury is the core of its pathological process. The pathological researches around cartilage damage have become more and more in- deepth, and the existing treatment cannot fundamentally reverse this process. However, with the development of cartilage tissue engineering technology in recent years, especially the use of mesenchymal stem cells has provided a new way to solve this difficulty. At the same time, the application of graphene materials in the medical field has gradually become popular. The use of graphene material properties as a scaffold structure combined with mesenchymal stem cells to seek a new method for cartilage damage repair, this paper will summarize the mechanism of knee cartilage injury, the repair of cartilage by mesenchymal stem cells and the application of graphene scaffold materials, in order to develop new treatment ideas.