某新建医院连续五年多重耐药菌目标性监测结果分析

目的 了解某新建医院多重耐药菌（MDRO）的分布特征及变化趋势，明确 MDRO 防控工作的重点。方法 收集郑州颐和医院2013年7月—2018年6月住院患者检出的目标性病原菌株，对其中分离的MDRO分布及变化趋势进行统计分析。结果 5年间共检出目标性病原菌7 395株，其中MDRO共812株。分离的MDRO中以耐碳青霉烯类鲍曼不动杆菌（CR-AB）居多（185株，22.78%），其次为耐碳青霉烯类肺炎克雷伯菌（CR-KP，180株，22.17%）。5年间MDRO总检出率为10.98%，年均检出率呈总体升高的趋势（χ2=20.245，P < 0.001）。MDRO感染类型以社区感染为主（535 例，65.89%），本院 MDRO 感染患者主要集中在神经外科、重症医学科、神经内科、呼吸科。结论 我院MDRO防控形势正随着开诊时间的延长而逐渐严峻，CR-AB和CR-KP的监测和管理是MDRO防控工作的重点。

Targeted surveillance analysis of multidrug-resisitance organisms in a new hospital for five consecutive years

Objective To understand the distribution characteristics and trends of multiple drug resistant organism (MDRO) in a new hospital, and to define the key point of MDRO prevention and control. Methods The target pathogen strains detected from inpatients in Zhengzhou Yihe hospital from July 2013 to June 2018 were collected, and the distribution and change trend of the isolated MDRO were analyzed. Results A total of 7 395 strains of targeted pathogens were detected, including 812 strains of MDRO. The majority of the isolated MDRO plants were carbapenems resistant acinetobacter baumannii (CR-AB, 185 plants, 22.78%), followed by carbapenems resistant Klebsiella pneumoniae (CR-KP,180 plants, 22.17%). The total detection rate of MDRO was 10.98% over the five-year, with an overall upward trend in the average annual detection rate (χ2=20.245, P < 0.001). The main type of MDRO infection was community infection (535 cases,65.89%), mainly concentrated in Neurosurgery, Critical Care, Neurology, and Respiratory Departments. Conclusion The prevention and control of multidrug resistant bacteria are gradually becoming more serious with the extension of the opening time in our hospital. Monitoring and management of CR-AB and CR-KP have become the focus of MDRO prevention and control.