| 肠道菌群在炎症相关肠癌中的研究进展 |
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| 引用本文： | 孔宪斌,王方园,彭莹莹,郭玉珠,孟静岩.肠道菌群在炎症相关肠癌中的研究进展[J].天津医药,2019,47(2):207-212. |
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| 作者姓名： | 孔宪斌 王方园 彭莹莹 郭玉珠 孟静岩 |
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| 作者单位： | 1天津中医药大学 （邮编301617）； 2天津市天津医院 |
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| 摘 要： | 炎症相关肠癌 （CAC） 是世界医学难题， 肿瘤微环境是目前研究的热点， 肠道菌群失调与CAC的发病密切
相关， 肠道菌群失调加重结肠炎诱导CAC的发生。随着微生态学的发展， 肠道菌群在CAC研究中备受关注。本文概
述了CAC发生过程中肠道菌群与饮食、 炎症机制、 肠黏膜的关系以及在诊断、 治疗中相关研究， 重点讨论了肠道菌群
可能成为CAC作用机制的新靶点和相关应用前景。
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| 关 键 词： | 炎症 肠肿瘤 饮食习惯 诊断 治疗 综述 炎症相关肠癌 |
| 收稿时间： | 2018-10-30 |
| 修稿时间： | 2018-12-06 |
Research progress of intestinal flora in colitis associated cancer |
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| KONG Xian-bin,WANG Fang-yuan,PENG Ying-ying,GUO Yu-zhu,MENG Jing-yan.Research progress of intestinal flora in colitis associated cancer[J].Tianjin Medical Journal,2019,47(2):207-212. |
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| Authors: | KONG Xian-bin WANG Fang-yuan PENG Ying-ying GUO Yu-zhu MENG Jing-yan |
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| Institution: | 1 Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; 2 Tianjin Hospital |
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| Abstract: | Colitis associated cancer (CAC) is a worldwide medical problem. Tumor microenvironment is the hot spot of current research. Intestinal flora imbalance is closely related to the incidence of CAC and aggravates colitis-induced CAC.
With the development of microecology, intestinal flora has received much attention in CAC research. This article outlines the
relationship between intestinal flora and diet, inflammatory mechanisms and intestinal mucosa during CAC development, and
the related research in diagnosis and treatment. It is mainly discussed that the intestinal flora may become a new target of
CAC mechanism and its related application prospects. |
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| Keywords: | inflammation intestinal neoplasms food habits diagnosis therapy review colitis associated cancer |
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