氟伏沙明联合认知行为治疗青少年抓痕障碍临床观察

目的 探讨氟伏沙明联合认知行为治疗青少年抓痕障碍的临床疗效。方法 选取医院2018年1月至2019年3月收治的青少年抓痕障碍患者34例,随机分为对照组和研究组,各17例。两组患者均予口服氟伏沙明片,研究组患者联合认知行为治疗。结果 与治疗前比较,两组患者治疗4周、12周后的耶鲁-布朗强迫症状量表(Y-BOCS)、儿童抑郁量表(CDI)和临床疗效总评量表(CGI)评分均显著降低(P<0.05),且研究组患者治疗12周后各量表评分显著低于对照组(P<0.05);两组患者副反应量表(TESS)评分无显著差异,仅个别患者出现轻度嗜睡和纳差。结论 氟伏沙明联合认知行为治疗青少年抓痕障碍的疗效优于单用氟伏沙明治疗。

Fluvoxamine Combined with Cognitive Behavior in the Treatment of Adolescent Skin Picking Disorder

Objective To observe the clinical efficacy of fluvoxamine combined with cognitive behavioral therapy on adolescent skin picking disorder(SPD).Methods Thirty-four adolescent SPD patients were randomly divided into the control group and study group,17 cases in each group.The control group received fluvoxamine only.The study group received fluvoxamine combined with cognitive behavioral therapy.Results Compared with before treatment,the scores of Yale-Brown Obsessive Compulsive Scale(Y-BOCS),Children’s Depression Inventory(CDI)and Clinical Global Impression(CGI)in the two groups were significantly reduced after 4 to 12 weeks of treatment(P<0.05),and the scores in the study group were significantly lower than those in the control group at 12 weeks(P<0.05);there was no significant difference in the scores of Treatment Emergent Symptom Scale(TESS)scores between the two groups;only a few patients had mild drowsiness and poor appetite.Conclusion Fluvoxamine combined with cognitive behavioral therapy is superior to fluvoxamine alone in the treatment of adolescent SPD.