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| 正交试验法优选胃力源胶囊的提取工艺 | |
| 引用本文： | 刘永忠,邵浩民,陈萍.正交试验法优选胃力源胶囊的提取工艺[J].中国药业,2009,18(16):42-43. |
| 作者姓名： | 刘永忠 邵浩民 陈萍 |
| 作者单位： | 1. 陕西省西安市中心医院药剂科,陕西,西安,710003 2. 西安新星药物研究所,陕西,西安,710065 3. 陕西省中医药研究院,陕西,西安,710003 |
| 摘 要： | 目的优选胃力源胶囊中白花蛇舌草、山楂的提取工艺。方法采用L9（3^4）正交试验设计法，以醇提浸膏得率、总有机酸含量、熊果酸含量为考察指标，优选乙醇浓度、乙醇用量、提取时间的最佳提取工艺条件。结果白花蛇舌草、山楂乙醇最佳提取工艺为药材用80％乙醇8倍量回流提取2次，每次2h，药渣再用水煎。结论该提取工艺合理，质量稳定，熊果酸等有效成分的提取率高。 |
| 关 键 词： | 正交试验 胃力源胶囊 白花蛇舌草 山楂 提取工艺 |
Optimal Extraction Technology of Weiliyuan Capsules by Orthogonal Method |
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| Liu Yongzhong,Shao Haomin,Chen Ping.Optimal Extraction Technology of Weiliyuan Capsules by Orthogonal Method[J].China Pharmaceuticals,2009,18(16):42-43. | |
| Authors: | Liu Yongzhong Shao Haomin Chen Ping |
| Institution: | 1. Department of Pharmacy, Xi＇an Central Hospital, Xi＇an, Shaanxi, China 710003; 2. Xi＇an New Star Research Institute of Chinese Medicine, Xi＇an, Shaanxi, China 710065; 3. Shaanxi Provincial Academy of Traditional Chinese Medicine, Xi＇an, Shaanxi, China 710003) |
| Abstract: | Objective To optimize the extraction technology of Herba Hedyotis Diffusae and hawthorn in Weiliyuan Capsules. Methods The extraction technology was optimized by orthogonal method with the extract rate of extractum, total organic acid and ursolic acid contents as the indexes. The influential factors for the extraction of effective ingredients included the concentration of ethanol, the volume of adding ethanol and the time of extraction. Results The best extraction technology was adding 8 times amount of 80% ethanol to medicinal herb, extracting twice and 2 h per time. Conclusion The extraction technology is reasonable with stable quality. The extraction rate of effective ingredients is high. |
| Keywords: | orthogonal method Weiliyuan Capsules Herba Hcdyotis Diffusae hawthorn extraction technique |
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