2012年医院101例急性化脓性阑尾炎治疗与用药分析

目的：调研2012年医院急性化脓性阑尾炎抗感染联合用药情况并进行点评，加强管理，促进合理用药。方法抽查2012年急性化脓性阑尾炎住院抗感染联合用药的治愈率（C）、人均住院天数（E）、人均日治疗金额J（F/D）、药品总金额占治疗总金额的比例I （ H/F ）、人均日药品金额G（H/D）、使用抗菌药物的比例M（L/A），单用及联用抗菌药物频率排序、抗菌药物占药品总金额（O）的比例，使用抗菌药物的人均治疗金额、合理用药数字化点评等。结果 C为99.01%，E为7.64 d，G为720.46元，I为44.65%，K为321.70元，M（抗菌药物使用比例）为100.00%，O（抗菌药物占药品总金额的比例）为54.30%，使用抗菌药的人均治疗金额Q为5506.86元，单用抗菌药物使用频率排序为头孢西丁及氨曲南、头孢美唑和奥硝唑；二联抗菌药物使用频率排序为奥硝唑氯化钠＋头孢西丁、奥硝唑氯化钠＋头孢美唑、奥硝唑氯化钠＋萘夫西林、依替米星＋奥硝唑、头孢西丁＋氨曲南、依替米星＋氨曲南；三联抗菌药物使用频率仅为9.90%，主要为依替米星＋氨曲南＋头孢西丁（或头孢美唑）、依替米星＋奥硝唑＋诺氟沙星（口服）等。结论医院急性化脓性阑尾炎手术伴感染用抗菌药物基本合理，但联合抗感染用药有优化或商榷余地，应加强合理用药指导和管理。

Treatment and Medication Analysis on 101 Cases of Acute Purulent Appendicitis in Our Hospital during 2012

Objective To investigate the combination use situation of anti-infection drugs in acute purulent appendicitis during 2012 and to conduct the comments for strengthening the management and promoting the reasonable use of drugs. Methods The spot check on the cure rate （ C ） , per capita hospitalization days （ E ） and daily cost J （ F/D ） ] , percentage of drugs cost in hospitalization charges I （ H/F ） , daily per capita drugs cost G （ H/D ） ] and proportion of anti-infection drugs use M （ L/A ） ] in 2012 was performed. Then, the frequency order for single use and combination use of anti-infection drugs, percentage of anti-infection drugs cost in the amount of drugs, per capita cost of anti-infection drugs and the reasonable use of drugs were commented. Resuts C was 99. 01%, E was 7. 64 d, G was 720. 46 Yuan, I was 44. 65%, K was 321. 70 Yuan, M was 100. 00%, O was 54. 30% and Q was 5 506. 86 Yuan. The frequen-cy order of single use of anti-infection drugs was cefoxitin sodium and aztreonam, cefmetazole sodium and ornidazoleo. The frequency order of bigeminy anti-infection drugs use was ornidazole sodium chloride＋cefoxitin, ornidazole sodium chloride＋cefmetazole, ornidazole sodium chloride＋nafcillin, etimicin＋ornidazole, cefoxitin＋aztreonam, etimicin＋aztreonam. The frequency of triple anti-infection drugs use was only 9. 90% , which mainly was etimicin＋aztreonam＋cefoxitin/cefmetazole, etimicin＋ornidazole＋norfloxacin （ oral ） , etc. Conclusion The anti-infection drugs use for the acute purulent appendicitis operation complicating infection is basically reasonable. But there is room to optimize and discuss the combination use of anti-infection drugs. The guidance and management of rational drug use should be strengthened.