| 格列喹酮与格列齐特的临床疗效及不良反应比较 |
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| 引用本文： | 廖彩霞,骆松梅,陈剑峰.格列喹酮与格列齐特的临床疗效及不良反应比较[J].中国药业,2011,20(3):52-53. |
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| 作者姓名： | 廖彩霞 骆松梅 陈剑峰 |
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| 作者单位： | 1. 浙江省丽水市中心医院,浙江,丽水,323000
2. 温州医学院,浙江,温州,325035 |
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| 摘 要： | 目的回顾性分析对比格列喹酮与格列齐特的临床疗效及不良反应。方法将丽水市中心医院内分泌科用过格列喹酮和格列齐特两种药物3个月以上的门诊和住院患者129例的病历资料及化验单进行统计分析,比较用药后空腹血糖、餐后2 h血糖及肝肾功能等指标。结果两组治疗3个月后空腹血糖均明显下降(P<0.05),格列齐特降空腹血糖效果优于格列喹酮,格列喹酮降餐后2 h血糖作用优于格列齐特;两组肝肾功能各项指标无大的波动,不良反应发生率无显著性差异。结论格列喹酮和格列齐特都有一定的降血糖疗效,格列喹酮不良反应较格列齐特少,且对肾功能具有一定的保护作用。
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| 关 键 词： | 格列喹酮 格列齐特 2型糖尿病 不良反应 |
Clinical Effect and Adverse Reaction of Gliquidone and Gliclazide |
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| Liao Caixia,Luo Songmei,Chen Jianfeng.Clinical Effect and Adverse Reaction of Gliquidone and Gliclazide[J].China Pharmaceuticals,2011,20(3):52-53. |
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| Authors: | Liao Caixia Luo Songmei Chen Jianfeng |
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| Institution: | Liao Caixia1,Luo Songmei1,Chen Jianfeng2(1.Lishui Central Hospital,Lishui,Zhejiang,China 323000,2.Wenzhou Medical College,Wenzhou,China 325035) |
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| Abstract: | Objective To review and analyze the clinical curative effect and adverse reaction of gliquidone and gliclazide.Methods One hundred and twenty-nine inpatients and outpatients in Lishui Center Hospital were statistically analyzed on medical records and lab reports in using gliquidone and gliclazide.To compare the indicators of FBG,2 h PBG,hepatorenal function.Results After 3 months of treatment,the FBG of gliquidone group and gliclazide group was significantly reduced(P < 0.05),and the gliclazide group was be... |
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| Keywords: | gliquidone gliclazide type 2 diabetes adverse reaction |
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