| 卡维地洛对冠心病伴焦虑患者的疗效观察 |
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| 引用本文： | 林钟文,吴盛标,吴胜楠,冯治西,黄志昕,杨鹏生,周其玲,胡赤怡,.卡维地洛对冠心病伴焦虑患者的疗效观察[J].医药世界,2005(12):55-56. |
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| 作者姓名： | 林钟文 吴盛标 吴胜楠 冯治西 黄志昕 杨鹏生 周其玲 胡赤怡 |
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| 作者单位： | [1]暨南大学附属第二临床医学院,518000 [2]深圳市人民医院心内科,518000 [3]深圳市康宁医院心理科,518000 |
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| 基金项目： | 深圳市科技局科研基金200204008赞助 |
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| 摘 要： | 目的 观察卡维地洛对冠心病伴焦虑患者的疗效,方法：用卡维地洛治疗冠心病伴有焦虑障碍（A组）30例，与不伴有焦虑障碍患者（B组）30例各8周，对两组治疗前后活动平板的运动耐量指标变化进行对照。结果：两组在治疗后的运动总步行时间，运动至心绞痛出现时间和运动到ST段压低达0．1mv，所需时间均较治疗前有明显延长（P〈0．05），但A组的效果比B组更显著（P〈0．05），尤其是病人症状出现的时间（P〈0．001），差别更大，A组的BAI评分改变更明显。结论：卡维地洛治疗冠心病伴有焦虑障碍的患者效果更显著。
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| 关 键 词： | 冠心病 焦虑 卡维地洛 运动试验 |
Efficacy of Carvedilol in Coronary Heart Disease with Anxiety |
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| LIN Zhongwen, Wu Shengbiao, Wushengnan, Feng Zhixie, Huan Zhixing, Yang Pengsheng, Zhou Qiling, Hu Cheyi..Efficacy of Carvedilol in Coronary Heart Disease with Anxiety[J].Medicine World,2005(12):55-56. |
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| Authors: | LIN Zhongwen Wu Shengbiao Wushengnan Feng Zhixie Huan Zhixing Yang Pengsheng Zhou Qiling Hu Cheyi |
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| Abstract: | Objective To evaluate whether Carvedilol is more beneficial in Coronary Heart Disease(CHD) withanxiety than without anxiety. Method CHD patients with anxiety (group A, n=30) and without anxiety(group B,n=30) were received Carvedilol for 8 weeks, the tolerance of exercise stress test was compared between these two groupbefore and after the trial. Result All cases showed a significant improvement in total exercise walking time, time to0.1mV ST-segment depression (p<0.05) after the combination therapy with carvedilol, which was more significant ingroup A than in group B(p<0.05), the time to onset of anginal was distinguish prolong (p<0.001). The Beck AnxietyInventory (BAI) in group A were changed more significant than group B (p<0.05). Conclusion In CHD with anxietytherapy with carvedilol get more significant effect than those without anxiety. |
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| Keywords: | Coronary heart disease Anxiety Carvedilol exercise stress test |
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