n-HA/PA66复合人工椎体对胸腰椎骨折结构重建的疗效观察

目的观察在胸腰段椎体骨折中行纳米羟基磷灰石/聚66（n-HA/PA66）复合生物活性人工椎体支撑植骨融合术后椎体结构重建作用和骨性融合作用。方法对31例胸腰椎骨折患者前路减压,采用n-HA/PA66复合生物活性人工椎体支撑植骨融合、钛板系统内固定。其中颈椎骨折5例,胸腰椎骨折26例。结果随访6～21个月（平均15个月）,植入体3～4个月产生骨融合,重建的椎体高度无降低,神经功能按Fankel分级均有不同程度提高。结论使用n-HA/PA66复合生物活性人工椎体植骨融合术,可有效恢复椎体的高度和结构,起到重建椎体结构作用,并能与椎体融合,保持良好的脊柱稳定性,是一种理想的椎体替代方式。

Observation of clinical effect of n-HA/PA66 composite artificial vertebral body reconstruction for the structure of thoracolumbar fractures

Objective Observed the reconstruction effect and bone fusion in thoracolumbar fracture of nano-hydroxyapatite/poly 66 （n-HA/PA66） composite biological activity after artificial vertebral interbody fusion.Methods 31 cases of thoracolumbar fractures in patients with anterior decompression using n-HA/PA66 complex biological activity supported by artificial vertebral body fusion and titanium plate fixation.Of which five cases of cervical spine fracture,26 cases of thoracolumbar fractures.Results All the patients get follow-up from 6 to 21 months（average 15 months） ,implant 3-4 months,resuhing in bone fusion, reconstruction of the vertebral body height of no lower grade neurological function in varying degrees according to Fankel increased. Conclusion Used n-HA/PA66 compound biological activity of artificial vertebral body fusion, which could effectively restored vertebral body height and structure,plaied a role in reconstruction of vertebral body structure, and with interbody fusion, maintaining good spinal stability,it was an ideal alternative kinds of vertebrae.