| 代谢组学及其在药学中的应用 |
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| 引用本文： | 蔡爽,孙博,李发美.代谢组学及其在药学中的应用[J].沈阳药科大学学报,2007,24(7):445-450. |
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| 作者姓名： | 蔡爽 孙博 李发美 |
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| 作者单位： | 沈阳药科大学,药学院,辽宁,沈阳,110016 |
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| 基金项目： | 高等学校博士学科点专项科研项目 |
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| 摘 要： | 目的对代谢组学(metabonomics)、代谢组学的主要研究方法和代谢组学在药学各领域中的应用作一综述。方法检索归纳相关文献35篇,按照代谢组学的基本思想、研究方法、在药学各领域的应用分类综述。结果代谢组学在药学领域中广泛应用于药物安全性评价、作用机制研究、新药的研发和中药的药效物质基础研究。
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| 关 键 词： | 代谢组学 代谢物 药学 |
| 文章编号： | 1006-2858（2007）07-0445-06 |
| 修稿时间： | 2006-10-08 |
Metabonomics and its applications in pharmacy |
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| CAI Shuang,SUN Bo,LI Fa-mei.Metabonomics and its applications in pharmacy[J].Journal of Shenyang Pharmaceutical University,2007,24(7):445-450. |
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| Authors: | CAI Shuang SUN Bo LI Fa-mei |
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| Institution: | School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China |
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| Abstract: | Objective To review the metabonomics and its applications in pharmacy. Methods Thirty-five related papers published in the last decade were summarized and the development, research methods and applications of metabonomics were introduced. Results and Conclusions Metabonomics is widely used in many fields, such as mechanism of drug action, drug toxicity screening, clinical safety and disease diagnosis. |
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| Keywords: | metabonomics metabolism pharmacy |
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