| 中药缓控释制剂的研究现状及研发思路 |
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| 引用本文： | 许海玉,张铁军,赵平,朱雪瑜,许浚.中药缓控释制剂的研究现状及研发思路[J].药物评价研究,2010(1):30-35. |
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| 作者姓名： | 许海玉 张铁军 赵平 朱雪瑜 许浚 |
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| 作者单位： | [1]天津中医药大学,天津300193 [2]天津药物研究院中药现代研究部,天津市中药质量控制技术工程实验室,天津300193 [3]天津药物研究院天津药代动力学与药效动力学省部共建国家重点实验室,天津300193 |
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| 基金项目： | “十一五”国家科技支撑计划资助项目（2006BAI06A01,2007BAI41B06） |
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| 摘 要： | 中药缓控释制剂研究起步较晚,发展也较慢,处在初级阶段,但近年来,中药复方缓控释制剂的研究报道逐年增加,研究广度和深度显著加强,已成为当前中药制剂研究的前沿和热点。现就中药缓释制剂的研究进展情况、制剂的类型进行综述并提出研究思路,为中药缓控释制剂的研究和开发提供参考。
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| 关 键 词： | 剂型 体外评价 药代动力学 纯化 中药缓释制剂 |
Research progress and ideas of sustained and controlled release preparation of traditional Chinese medicine |
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| XU Hai-yu,ZHANG Tie-Jun ZHAO Ping ZHU Xue-yu,XU Jun.Research progress and ideas of sustained and controlled release preparation of traditional Chinese medicine[J].Drug Evaluation Research,2010(1):30-35. |
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| Authors: | XU Hai-yu ZHANG Tie-Jun ZHAO Ping ZHU Xue-yu XU Jun |
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| Institution: | 1 Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; 2 Tianjin Research Center of Modem Chinese Medicines, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China; 3 Tianjin State Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China) |
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| Abstract: | Research on sustained and controlled release preparation of traditional Chinese medicine is in primary stage now because of its start late and its development slow. But the amount of the reports increase year by year, the scope become more and more wide and the depth get more and more deep in recent years. In order to study and to exploitate them, we summarize research progress about drug study, dosage form and in vitro evaluation of sustained release preparation of CMM and research ideas of sustained release preparation of CMM in this text. |
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| Keywords: | dosage form in vitro evaluation pharmacokinetics purification sustained and controlled release preparation of Chinese materia medica |
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