| 注射用头孢拉定和缩宫素注射液配伍的稳定性研究 |
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| 引用本文： | 陈卫民,江国荣.注射用头孢拉定和缩宫素注射液配伍的稳定性研究[J].现代食品与药品杂志,2014(3):213-215. |
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| 作者姓名： | 陈卫民 江国荣 |
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| 作者单位： | 广东省佛山市第一人民医院药剂科,广东佛山528000 |
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| 摘 要： | 目的考察注射用头孢拉定和缩宫素注射液配伍的稳定性。方法在20℃下8h内考察注射用头孢拉定和缩官素注射液配伍后，其混合溶液的外观及不溶性微粒变化，并用高效液相色谱法测定药物的含量。结果注射用头孢拉定和缩宫素注射液配伍后，8h内药物的含量、混合溶液的外观及不溶性微粒均无明显变化。结论注射用头孢拉定和缩宫素注射液不存在理化性的配伍禁忌。
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| 关 键 词： | 注射用头孢拉定 缩宫素注射液 高效液相色谱法 配伍禁忌 稳定性 |
Compatible Stability of Cefradine for Injection and Oxytocin Injection |
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| CHEN Wei-min,JIANG Guo-rong.Compatible Stability of Cefradine for Injection and Oxytocin Injection[J].JOurnal of Modern Food and Pharmaceuticals,2014(3):213-215. |
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| Authors: | CHEN Wei-min JIANG Guo-rong |
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| Institution: | ( Foshan No. 1 People＇s Hospital, Foshan, Guangdong 528000, China) |
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| Abstract: | Objective To study the compatible stability of cefradine for injection when it was combined with oxytocin injection. Methods The change of appearance and indissoluble particle in the mixture within 8 h at 20 ℃ were observed after cefradine for injection being combined with oxytocin injection. The contents of drugs were determined by HPLC. Results No significant change was found in content, appearance and indissoluble pa：icle in 8 h after cefradine injection being combined with oxytocin injection. Conclusion There is no physical and chemical compatibility taboo when cefradine for injection is combined with oxytocin injection. |
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| Keywords: | cefradine for injection oxytocin injection HPLC compatibility taboo stability |
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