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| 小果蔷薇化学成分的研究 | |
| 引用本文： | 包海燕,苗青,沈阳,朴淑娟,宋少江,林厚文,吴兴文.小果蔷薇化学成分的研究[J].药学实践杂志,2009,27(2):101-103. |
| 作者姓名： | 包海燕 苗青 沈阳 朴淑娟 宋少江 林厚文 吴兴文 |
| 作者单位： | 1. 第二军医大学长征医院药学部,上海,200003;沈阳药科大学中药学院,辽宁,沈阳,110016 2. 第二军医大学长征医院药学部,上海,200003 3. 沈阳药科大学中药学院,辽宁,沈阳,110016 4. 上海市阐北区中心医院药剂科,上海,200070 |
| 基金项目： | 重大新药创制科技重大专项基金 |
| 摘 要： | 目的：研究小果蔷薇Rosa cymosa Tratt．中的化学成分。方法：运用多种色谱方法对小果蔷薇中的化学成分进行分离，根据理化性质和波谱数据分析进行结构鉴定。结果：分离得到6个化合物，分别为β-谷甾醇（1），2α-羟基乌苏酸（2），蔷薇酸（3），胡萝卜苷（4），紫云英苷（5），翻白叶苷A（6）。结论：化合物1～6均为从小果蔷薇中首次分离得到。 |
| 关 键 词： | 小果蔷薇 化学成分 提取分离 结构鉴定 |
| 收稿时间： | 5/8/2008 12:00:00 AM |
Studies on chemical constituents of Rosa cymosa |
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| BAO Hai-yan,MIAO Qing,SHEN Yang,PIAO Shu-juan,SONG Shao-jiang,LIN Hou-wen and WU Xing-wen.Studies on chemical constituents of Rosa cymosa[J].The Journal of Pharmaceutical Practice,2009,27(2):101-103. | |
| Authors: | BAO Hai-yan MIAO Qing SHEN Yang PIAO Shu-juan SONG Shao-jiang LIN Hou-wen and WU Xing-wen |
| Institution: | Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China;Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China;School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China;Department of pharmacy, Shanghai Zhabei District Central Hospital, Shanghai 200070, China |
| Abstract: | Objective： To investigate the chemical constituents of Rosa cymosa. Methods： Multi-chromatographic methods were employed for the isolation and purification of Rosa cymosa. The structures were identified on the basis of chemical evidence and spectral data. Results：Six compounds were isolated and identified as β-sitosterol （1）, 2α-hydroxyursolic acid （2）, euscaphic acid （3）, daucosterol （4）, kacmferol-3-O-β-D-glucoside （5） , potengriffioside A （6）. Conclusion：Compounds 1 - 6 were all isolated from Rosa cymosa for the first time. |
| Keywords: | Rosa cymosa chemical constituents |
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