| 复方甲硝唑凝胶的研制 |
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| 引用本文： | 王增福,朱全刚,王雯佶,胡晋红,刘荔荔,朱臻宇.复方甲硝唑凝胶的研制[J].药学实践杂志,1996(5). |
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| 作者姓名： | 王增福 朱全刚 王雯佶 胡晋红 刘荔荔 朱臻宇 |
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| 作者单位： | 上海第二军医大学长海医院药学部，第二军医大学药学院药分教研室 |
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| 摘 要： | 复方甲硝唑凝胶是以卡波姆９４０为基质的水溶性透明凝胶，主要成分为甲硝唑、地塞米松磷酸钠，可用于治疗口腔溃疡和牙周炎等。本文介绍了复方甲硝唑凝胶的处方组成、制备方法、含量测定和质量标准。凝胶中甲销唑和地塞米松的含量采用褶合曲线分析法不经分离同时测定，操作简单、快速。
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| 关 键 词： | 甲硝唑 地塞米松磷酸钠 凝胶 褶合曲线分析法 |
The preparation of compound metronidazole gel |
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| Wang Zengfu,Zhu Quangang,Wang Wengji,Hu Jinhong,Liu Lili,Zhu Zhenyu.The preparation of compound metronidazole gel[J].The Journal of Pharmaceutical Practice,1996(5). |
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| Authors: | Wang Zengfu Zhu Quangang Wang Wengji Hu Jinhong Liu Lili Zhu Zhenyu |
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| Abstract: | The gel of compound metronidazole is at ransparent hydrophilic gel of carbomer 940,which consist of metronidazole and dexamethasone sodium phosphate.It is used topically to treat aphthous ulcer and peridental inflammation.We reported the preformulation,method of preparation,quantitative determination and the standard for quality of the gel in this paper.The metronidazole and dexamethasone sodium phosphate in the gel were analysed by the computer-aided convolution cure method without prior separation.These methods are simple and rapid. |
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| Keywords: | metronidazole dexamethasone sodium phosphate gel convolution curve method |
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