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星点设计-效应面法优化酒制巴戟天的炮制工艺
引用本文:张成中,万赫,蒋益萍,贾丹,冯坤苗,辛海量.星点设计-效应面法优化酒制巴戟天的炮制工艺[J].药学实践杂志,2020,38(5):447-450.
作者姓名:张成中  万赫  蒋益萍  贾丹  冯坤苗  辛海量
作者单位:海军军医大学药学院中药鉴定学教研室,上海 200433;海军军医大学药学院生药学教研室,上海 200433
基金项目:海军院校建设项目(XLTJ2018009)
摘    要:目的 以水晶兰苷为指标建立酒制巴戟天最佳炮制工艺。方法 采用星点设计-效应面法以辅料黄酒用量、润药时间为考察因素,水晶兰苷的含量变化为评价指标,优化酒蒸巴戟天的炮制工艺。结果 星点设计-效应面法优化酒制巴戟天的最佳炮制工艺为:辅料黄酒用量为10%(g/g)、浸润时间为1 h,蒸透,干燥。结论 以黄酒用量、浸润时间为考察因素,水晶兰苷为评价指标的响应面法能够用于优化酒蒸巴戟天的最佳炮制工艺。

关 键 词:效应面法  巴戟天  酒制  炮制工艺
收稿时间:2020/3/29 0:00:00
修稿时间:2020/5/29 0:00:00

Process optimization of Morinda officinalis with wine steaming by star dot design-response surface methodology
ZHANG Chengzhong,WAN He,JIANG Yiping,JIA Dan,FENG Kunmiao,XIN Hailiang.Process optimization of Morinda officinalis with wine steaming by star dot design-response surface methodology[J].The Journal of Pharmaceutical Practice,2020,38(5):447-450.
Authors:ZHANG Chengzhong  WAN He  JIANG Yiping  JIA Dan  FENG Kunmiao  XIN Hailiang
Institution:Department of Identification of Traditional Chinese Medicine, School of Pharmacy, Naval Medical University, Shanghai 200433, China;Department of Pharmacognosy, School of Pharmacy, Naval Medical University, Shanghai 200433, China
Abstract:Objective To establish the best wine steaming process for morinda officinalis with monotropein as indicator.Methods Response surface methodology was used to optimize the wine steaming process for morinda officinalis with the amount of rice wine, stewing time, moistening time and the monotropein content as evaluation indexes.Results The best condition was identified with rice wine (rice wine/herbs, g/g) 10%, moistening time 1.0 h, fully steamed and dried.Conclusion The Star dot design-response surface method can be used to optimize the wine steaming process for morinda officinalis.
Keywords:star dot design-response surface methodology  Morinda officinali  wine steaming  processing technology
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