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| 中药金樱子的化学成分研究 | |
| 引用本文： | 吴兴文,高品一,李玲芝,陆祎,沈阳,宋少江,林厚文.中药金樱子的化学成分研究[J].药学实践杂志,2009,27(3):183-185. |
| 作者姓名： | 吴兴文 高品一 李玲芝 陆祎 沈阳 宋少江 林厚文 |
| 作者单位： | 1. 上海市闸北区中心医院药剂科,上海,200070 2. 沈阳药科大学中药学院,辽宁,沈阳,110016 3. 第二军医大学长征医院药学部,上海,200003 |
| 基金项目： | 国家科技重大专项基金 |
| 摘 要： | 目的：研究金樱子Rosa laevigata Michx．果实的化学成分。方法：运用正反相硅胶，凝胶（Sephadex LH-20）等多种柱色谱进行分离纯化，根据理化性质和波谱数据进行结构鉴定。结果：分离得到5个化合物，经鉴定分别为2α，3β，19α-三羟基齐墩果酸（Ⅰ），山奈酚（Ⅱ），翻白叶苷A（Ⅲ），β-谷甾醇（Ⅳ），胡萝卜亭（Ⅴ）。结论：化合物Ⅰ为首次从金樱子果实中分离得到。 |
| 关 键 词： | 金樱子 化学成分 提取分离 结构鉴定 |
| 收稿时间： | 5/5/2008 12:00:00 AM |
Studies on the chemical constituents of Rosa laevigata Michx fruits |
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| WU Xing-wen,GAO Pin-yi,LI Ling-zhi,LU Yi,SHEN Yang,SONG Shao-jiang and LIN Hou-wen.Studies on the chemical constituents of Rosa laevigata Michx fruits[J].The Journal of Pharmaceutical Practice,2009,27(3):183-185. | |
| Authors: | WU Xing-wen GAO Pin-yi LI Ling-zhi LU Yi SHEN Yang SONG Shao-jiang and LIN Hou-wen |
| Institution: | Department of Pharmacy, Shanghai Zhabei District Central Hospital, Shanghai 200070, China;School of Traditional Chinese Materia Medica, Shenyang Pharmercutical University, Shenyang 110016, China;School of Traditional Chinese Materia Medica, Shenyang Pharmercutical University, Shenyang 110016, China;School of Traditional Chinese Materia Medica, Shenyang Pharmercutical University, Shenyang 110016, China;Department of Pharmacy, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China;School of Traditional Chinese Materia Medica, Shenyang Pharmercutical University, Shenyang 110016, China;Department of Pharmacy, Shanghai Zhabei District Central Hospital, Shanghai 200070, China |
| Abstract: | Objective： To investigate the chemical constituents from fruits of Rosa laevigata Michx fruits. Methods ： Multi-chrom- atographic methods including Silica gel column chromatography and Sephadex LH-20 gel permeation were employed for the isolation and purification. The structures were identified on the basis of chemical evidence and spectral data. Results ： Five compounds were isolated and identified as： 2α, 3β, 19α-trihydroxyolean-12-en-28-oic acid（ Ⅰ ）, kaempferol（ Ⅱ ） , potengriffioside A（ Ⅲ ） , β-sitosterol（ Ⅳ ） , daucosterol（ Ⅴ）. Conclusions：Compound Ⅰwas isolated from fruits of Rosa laevigata Michx for the first time. |
| Keywords: | Rosa laevigata Michx chemical constituents isolation structure identification |
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