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FTY720 Inhibits MPP+-Induced Microglial Activation by Affecting NLRP3 Inflammasome Activation |
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| Authors: | Yao Shu Li Longjun Sun Xin Hua Jun Zhang Keqi Hao Li Liu Lixin Shi Dongyan Zhou Hong |
| Institution: | 1.Department of Immunology, Nanjing Medical University, 101 Longmian Avenue, Nanjing, 211166, JS, China ;2.Department of Clinical Pharmacy, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, No. 1, Fuhua Road, Futian District, Shenzhen, 518033, Guangdong, China ;3.Institute of Microscope Science and Technology, Ningbo Yongxin Optics Co. Ltd., 385 Mingzhu Road, Hi-tech Industry Park, Ningbo, 315040, China ;4.Department of Anatomy, Physiology and Pharmacology, College of Medicine, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK, S7N 5E5, Canada ;5.Department of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, 210011, Jiangsu, China ; |
| Abstract: | Journal of Neuroimmune Pharmacology - Parkinson’s disease (PD) is characterized by the degeneration of dopaminergic neurons and excessive microglial activation in the substantia nigra pars... |
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