甘精胰岛素治疗1型糖尿病16例临床体会 |
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引用本文: | 柴杰.甘精胰岛素治疗1型糖尿病16例临床体会[J].中国医药,2006,4(1):513-514. |
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作者姓名: | 柴杰 |
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作者单位: | 广东省深圳市第二人民医院内分泌科,518035; |
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摘 要: | Objective To observe the effect of glargine for treatment of type 1 diabetes. Methods Sixteen type 1 diabetes patients were randomized in two groups. In the Glargine group, 10 patients were given injection Nov-olin R before every meal and injection Glargine at bedtime daily. Meanwhile 6 patients in the NPH group were given injection Novolin R before every meal and injection NPH at bedtime daily. The dosage of insulin was adjusted by blood glucose level, seeking a target of FBG ≤6.5 mmol/L and 2 h PBG≤10.0 mmoL/L. The blood glucose level and incidence of hypoglycemia were observed. Results Mean blood glucose level was similiar in the 2 groups(P > 0.10), but the incidence of hypoglycemia in the Glargine group was significantly lower than that in the NPH group (P < 0.05). Conclusion Glargine initiates the physiological secretion of insulin and controls the blood glucose lev-el more effectively.
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关 键 词: | 1型糖尿病 甘精胰岛素 胰岛素强化治疗 |
Glargine for treatment of type 1 diabetes |
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Abstract: | |
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Keywords: | Type 1 diabeticGlargineIntensive insulin therapy |
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