| 近红外光谱相似度用于中药提取物质量控制方法的研究 |
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| 引用本文： | 潘建超,薛东升.近红外光谱相似度用于中药提取物质量控制方法的研究[J].中国医药工业杂志,2011,42(5). |
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| 作者姓名： | 潘建超 薛东升 |
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| 作者单位： | 上海凯宝药业股份有限公司,上海,201400 |
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| 摘 要： | 建立了一种基于近红外光谱相似度的中药提取物质量控制方法.从5种中药提取物中随机划分校正集与验证集,取与校正集样品平均光谱的相似度大于99%的样品作为标准样品库,建立相似度计算模型.利用所建模型预测样品近红外光谱的相似度.结果显示:相似度较高的样品,其含量测定数据也较接近平均值.而且近红外光谱还能够反映提取物样品除有效成分含量之外的差异.
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| 关 键 词： | 近红外光谱 相似度 中药提取物 质量控制 |
Quality Control of Traditional Chinese Medicine Extracts by NIR Spectra Similarity |
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| Authors: | PAN Jianchao XUE Dongsheng |
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| Institution: | PAN Jianchao,XUE Dongsheng(Shanghai Kaibao Pharmacy Co.,Ltd.,Shanghai 201400) |
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| Abstract: | A near infrared(NIR) spectra similarity method was established for the quality control of traditional Chinese medicine(TCM) extracts.Five kinds of TCM extract samples were randomly divided into calibration set and validation set.The samples from the calibration set,which have the similarity above 99% with the average spectrum,were served as the standard sample library,and the models for the similarity calculating were established.The NIR spectra similarities of the validation set samples were calculated usi... |
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| Keywords: | near infrared spectrum similarity traditional Chinese medicine extract quality control |
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