纳米混悬剂的制备方法及在药剂学中应用的研究进展 |
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引用本文: | 朱建芬,吴祥根.纳米混悬剂的制备方法及在药剂学中应用的研究进展[J].中国医药工业杂志,2006,37(3):196-200. |
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作者姓名: | 朱建芬 吴祥根 |
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作者单位: | 1. 青岛市食品药品监督管理局,山东,青岛,266001 2. 军事医学科学院毒物药物研究所,北京,100850 |
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摘 要: | 纳米混悬剂可增大难溶性药物的溶解度,改变药物的体内动力学特征,提高安全性和有效性。综述了纳米混悬剂的制各方法及其在药剂学中应用的研究进展。
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关 键 词: | 纳米混悬剂 难溶性药物 粒径 溶解度 综述 |
文章编号: | 1001-8255(2006)03-0196-05 |
收稿时间: | 2005-05-16 |
修稿时间: | 2005-05-16 |
Progress of the Preparation and Applications in Pharmaceutics of Nanosuspensions |
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Authors: | ZHU Jian-Fen WU Xiang-Gen |
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Institution: | 1. Qingdao Food and Drug Administration, Qingdao 266001; 2. Institute of Pharmacology and Toxicology, the Academy of Military Medical Science, Beijing 100850 |
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Abstract: | Nanosuspensions can increase the solubility of insoluble drugs, change the pharmacokinetics and improve safety and efficacy. The progress of the preparation and applications in pharmaceutics of nanosuspensions is reviewed. |
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Keywords: | nanosuspension insoluble drug particle size solubility review |
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