碘普罗胺注射液不良反应的文献计量分析

目的从文献计量学角度评估碘普罗胺注射液不良反应发生的一般规律和特点。方法以＂碘普罗胺和（或）优维显＂、＂不良反应和（或）过敏＂为主题词,检索中国生物医学全文数据库（CBM）,中国知网数据库（CNKI）,维普全文期刊数据库（VIP）和万方数据库（WF）,对纳入研究的文献进行统计分析。结果有42篇文献纳入研究,发表自14个省级行政区,被29种期刊收录;碘普罗胺注射液不良反应的发生以50 a以上患者为主,且多为全身性损害。结论临床上应用碘普罗胺注射液时,应密切观察该年龄段患者的用药反应,并准备好相应的应急药物和设施,确保用药安全。

Bibliometric Analysis of Iopromide Injection-Induced Adverse Drug Reaction

Objective To evaluate the general patterns and characterisitics of Iopromide injection-induced adverse drug reaction（ ADR） by bibliometric analysis. Methods All publications about ＂Iopromide injection＂and /or ＂Ultravist＂,＂adverse drug reaction＂and/or＂allergic＂were collected from CBM,CNKI,VIP,and WF data. Bibliometrical analysis was performed according to the publication years,addresses,agencies and things about case report. Results A total of 53papers were included. Articles were collected from 14 provinces and autonomous regions and 29 journals. The ADR of Iopromide injection was more for systemic damage. The age of patients was main over 50. Conclusion The reactions should be closely observed in the clinical application of Iopromide injection,and the appropriate emergency drugs and facilities should be prepared for patients’ safety.