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Global sensitivity analysis in physiologically-based pharmacokinetic/pharmacodynamic models of inhaled and opioids anesthetics and its application to generate virtual populations
Authors:Sánchez Restrepo  Frank  Hernández Valdivieso  Alher Mauricio
Institution:1.Bioinstrumentation and Clinical Engineering Research Group - GIBIC, Bioengineering Program, Bioengineering Department, Engineering Faculty, Universidad de Antioquia UdeA, Calle 70, No. 52-21, 050016, Medellín, Colombia
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Abstract:Journal of Pharmacokinetics and Pharmacodynamics - The integration between physiologically-based pharmacokinetics (PBPK) models and pharmacodynamics (PD) models makes it possible to describe the...
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