Global sensitivity analysis in physiologically-based pharmacokinetic/pharmacodynamic models of inhaled and opioids anesthetics and its application to generate virtual populations
1.Bioinstrumentation and Clinical Engineering Research Group - GIBIC, Bioengineering Program, Bioengineering Department, Engineering Faculty, Universidad de Antioquia UdeA, Calle 70, No. 52-21, 050016, Medellín, Colombia ;
Abstract:
Journal of Pharmacokinetics and Pharmacodynamics - The integration between physiologically-based pharmacokinetics (PBPK) models and pharmacodynamics (PD) models makes it possible to describe the...