| 木犀草素缩苯胺席夫碱配合物的合成及抑菌活性 |
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| 引用本文： | 沙靖全,李敬芬,闫红.木犀草素缩苯胺席夫碱配合物的合成及抑菌活性[J].黑龙江医药科学,2004,27(6):11-12. |
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| 作者姓名： | 沙靖全 李敬芬 闫红 |
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| 作者单位： | 1. 佳木斯大学化学与药学院,黑龙江,佳木斯,154007
2. 浙江湖州师范学院,浙江,湖州,313000 |
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| 基金项目： | 黑龙江省教育厅资助项目 |
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| 摘 要： | 目的：基于木犀草素的生物活性和席夫碱的特有性质基础上，设计与金属形成一系列新型席夫碱金属配合物。方法：利用缩合反应，在无水乙醇中合成未见报道的黄酮类席夫碱过渡金属配合物。并通过元素分析、紫外光谱、红外光谱、摩尔电导等手段对其进行了结构表征和抗菌活性实验。结果：通过分析，初步确定了其分子式、结构和其．生物活性。结论：结构式为：配合物MLx．nC2H5OH。形成配合物后抑菌活性大大增强。
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| 关 键 词： | 席夫碱 金属配合物 抗菌活性 |
| 文章编号： | 1008-0104(2004)06-0011-02 |
| 修稿时间： | 2004年10月14 |
Syntheses and antibacterial activity of metal-complexes of luteolin schiff base |
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| SHA Jing-quan ,LI Jing-fen ,YAN Hong.Syntheses and antibacterial activity of metal-complexes of luteolin schiff base[J].Heilongjiang Medicine and Pharmacy,2004,27(6):11-12. |
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| Authors: | SHA Jing-quan LI Jing-fen YAN Hong |
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| Institution: | SHA Jing-quan 1,LI Jing-fen 2,YAN Hong 1 |
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| Abstract: | Objective: To design and synthesize a new type of schiff base and its complexes on the basis of luteolin bioactivity and schiff base traits. Method: A series of metal-complexes were synthesized by using condensation reaction. These compounds were characterized by elemental analysis, ultraviolet spectra, infrared spectra, molar conductance, and their antibacterial activity experiment was done. Result: Their ingredients and molecular structural formula and antibacterial activity were determined. Conclusion: The structure formula is ML x.nC 2H 5OH which has a high antibacterial activity. |
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| Keywords: | schiff base metal-complexes antibacterial activity |
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