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盐酸左氧氟沙星与4种注射液在输液中的配伍稳定性
引用本文:沈云玉,任鹏.盐酸左氧氟沙星与4种注射液在输液中的配伍稳定性[J].抗感染药学,2006,3(1):32-33,39.
作者姓名:沈云玉  任鹏
作者单位:苏州市第四人民医院,江苏,苏州,215001
摘    要:目的:考察盐酸左氧氟沙星在葡萄糖输液中与4种注射液(消旋山莨菪碱、地塞米松、氯化钾、维生素C)的配伍稳定性。方法:采用紫外分光光度法考察盐酸左氧氟沙星与上述4种注射液配伍后室温下6h内的含量变化情况,同时观察外观并测定pH值。结果:在室温条件下,盐酸左氧氟沙星注射液与上述药物配伍0~6h内其外观、pH值及含量均无显著变化。结论:6h内盐酸左氧氟沙星与上述4种注射液在葡萄糖输液中配伍基本稳定。

关 键 词:盐酸左氧氟沙星  消旋山莨菪碱  地塞米松  氯化钾  维生素C  配伍稳定性
文章编号:1672-7878(2006)01-0032-02
收稿时间:2005-05-22
修稿时间:2005-05-222005-10-07

Compatibility Stability of Levofloxacin Hydrochloride with Four Kinds of Injection in Transfusion
SHEN Yun-Yu,REN Peng.Compatibility Stability of Levofloxacin Hydrochloride with Four Kinds of Injection in Transfusion[J].Anti-infection Pharmacy,2006,3(1):32-33,39.
Authors:SHEN Yun-Yu  REN Peng
Abstract:Objective:To study the stability of levofloxacin hydrochloride mixed with four kinds of injection (raceanisodamine, dexamethasone,potassium chloride,vitamin C) in glucose injection solution.Methods:Ultraviolet spectro- photometry and pH meter were used to investigate the compatible content of levofloxacin hydrochloride with above mentioned four kinds of injection,and determination pHof compatible solution in room temperature within 6 h.Results:When the levofloxacin hydrochloride was mixed with above mentioned four kinds of injection within 0-6 h under room temperature , the appeance,pH and its content have no obvious change. Conlusion : Levofloxacin hydrochloride mixed with four kinds of injection in glucose injection is basically stable.
Keywords:Levofloxacin hydrochloride  Raceanisodamine  Dexamethasone  Potassium chloride  Stability
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