| 抗菌植物甾体及其生物合成的研究进展 |
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| 引用本文： | 王秋军,王剑文.抗菌植物甾体及其生物合成的研究进展[J].抗感染药学,2012,9(2):86-91. |
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| 作者姓名： | 王秋军 王剑文 |
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| 作者单位： | 苏州大学药学院,江苏苏州,215123 |
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| 基金项目： | 国家教育部留学基金，苏州大学东吴学者计划，江苏省六大人才高峰项目 |
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| 摘 要： | 植物甾体化合物是一类具有抗菌生物活性的天然产物,其生物合成主要通过甲羟戊酸途径与5-磷酸脱氧木酮糖/2C-甲基-4-磷酸-4D-赤藓糖醇的途径,对其合成途径的研究是调控甾体类抗菌药物生产的关键。综述了植物甾体化合物的抗菌活性和生物合成途径的研究近况。
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| 关 键 词： | 植物甾体 抗菌活性 生物合成途径 关键酶 |
Recent Research Advances on Antimicrobial Activities and Biosynthesis of Phytosteroids |
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| WANG Qiu-jun
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WANG Jian-wen.Recent Research Advances on Antimicrobial Activities and Biosynthesis of Phytosteroids[J].Anti-infection Pharmacy,2012,9(2):86-91. |
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| Authors: | WANG Qiu-jun WANG Jian-wen |
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| Institution: | *3 School of Pharmaceutical Sciences,Soochow University,Suzhou Jiangsu 215123,China |
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| Abstract: | Phytosteroids are main plant constituents of antimicrobial activities.They are synthesized in plants via the mevalonate(MVA) pathway and the methylerythritol phosphate(MEP) pathway.It is of great importance for the production of antimicrobial phytosteroids to understand their biosynthetic pathway.This review gives a summary of the recent explorations on antimicrobial activities and biosynthetic pathways of phytosteroids. |
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| Keywords: | phytosteroid antimicrobial activities biosynthetic pathways key enzymes |
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