| 冰片在不同贮存条件下稳定性的考察 |
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| 引用本文： | 张真真,;王岩,;张振海,;倪孟祥,;尹鸿萍.冰片在不同贮存条件下稳定性的考察[J].抗感染药学,2014(3):195-197. |
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| 作者姓名： | 张真真 ;王岩 ;张振海 ;倪孟祥 ;尹鸿萍 |
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| 作者单位： | [1]中国药科大学,生命科学与技术学院,江苏南京210009; [2]江苏省中医药研究院,中药新型给药系统重点实验室,江苏南京210028 |
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| 摘 要： | 目的：考察冰片在不同贮存条件下的稳定性,为冰片的贮存条件提供参考。方法：建立毛细管柱气相色谱法测定冰片中龙脑的含量,并系统考察在密闭条件下的光照、温度和空气对合成冰片稳定性的影响。结果：将冰片密闭贮存12月,其龙脑的含量仍大于55%,而樟脑的含量未检测;在低温、充氮和避光保存,其龙脑的含量比高温、不充氮和光照的含量高。结论：冰片经密闭贮存12月,龙脑的含量是保证的,且温度、空气和光照对冰片的稳定性有影响。
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| 关 键 词： | 气相色谱法 冰片 龙脑 光照 温度 空气 稳定性 |
Study on Stability of Borneol under Different Storage Conditions |
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| Institution: | ZHANG Zhen-zhen, WANG Yan, ZHANG Zhen-hai, NI Meng-xiang, YIN Hong-ping(1 School of Life Science and Technology, China Pharmaceutical University Nanjing 210009, China ;2Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Academy of TCM ,Nanjing 210028, China) |
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| Abstract: | Objective： To study the stability of Borneol under different storage conditions, and to provide a reference for bomeol storage. Methods： Establishing capillary column gas chromatography to measure the content of Borneel, and systematically investigating the effects of synthetic Borneol sealed under conditions of light, temperature and air. Results： The content of Camphol is still greater than 55% after airtight for 12 months, while the content of Camphor is not detected. The content of Camphol at low temperature and under nitrogen-filled and lucifugal preservation is greater than that at high temperature, nitrogen-unfilled and irradiant. Conclusion： The content of Camphol can be guaranteed alter Borneol sealed for a year. The temperature, nitrogen and light have an impact on the stability of Borneol. |
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| Keywords: | gas chromatography Borneol camphol light air temperature stability |
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