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头孢美唑与奥硝唑氯化钠注射液配伍的稳定性考察
引用本文:钱金娥,曹剑波,许晓东.头孢美唑与奥硝唑氯化钠注射液配伍的稳定性考察[J].抗感染药学,2009,6(3):177-179.
作者姓名:钱金娥  曹剑波  许晓东
作者单位:张家港市第一人民医院,江苏,张家港,215600
摘    要:目的:考察注射用头孢美唑与奥硝唑/氯化钠注射液配伍后的稳定性。方法:采用紫外分光光度法测定注射用头孢美唑与奥硝唑/氯化钠注射液配伍后的质量浓度,同时观察配伍液的外观性状变化,并测定pH值。结果:室温条件下8h内配伍液的外观性状、pH值及头孢美唑与奥硝唑的质量浓度均无明显变化。结论:注射用头孢美唑与奥硝唑/氯化钠注射液在临床应用中可配伍使用。

关 键 词:头孢美唑  奥硝唑  氯化钠  稳定性

Studies on Stability of Cefmetazole Sodium for Injection Mixed with Ornidazole and Sodium Chloride Injection
QIAN Jin-e,CAO Jian-bo,XU Xiao-dong.Studies on Stability of Cefmetazole Sodium for Injection Mixed with Ornidazole and Sodium Chloride Injection[J].Anti-infection Pharmacy,2009,6(3):177-179.
Authors:QIAN Jin-e  CAO Jian-bo  XU Xiao-dong
Institution:( The No.1 People's Hospital of Zhangjiangang, Zhangjiagang Jiangsu 215600, China)
Abstract:Objectives: To study the stability of cefmetazole sodium for injection mixed with ornidazole and sodium chloride injection. Methods: Content changes of the mixed solution of ornidazole sodium chloride injection with cefmetazole were detected at different time by ultraviolet spectrophotometry and the pH value, the appearance and the insoluble microparticles of the solution were also detected. Results: The contents, external appearance and PH value of the mixed solution showed no significant changes within 8h.Conclusion: Cefinetazole Injection mixed with omidazole sodium chloride injection could be kept stable within 8 h.
Keywords:cefmetazole  ornidazole  sodium chloride  stability
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