| 灯盏花素防治急性脑梗死作用机制及应用进展 |
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| 引用本文： | 何苗,李敏清,文曦娜,李淑娟,伍友琼,许建综,耿家斌. 灯盏花素防治急性脑梗死作用机制及应用进展[J]. 中国医药科学, 2012, 0(22): 30-31,54 |
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| 作者姓名： | 何苗 李敏清 文曦娜 李淑娟 伍友琼 许建综 耿家斌 |
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| 作者单位： | 四川省达州市中心医院中医科 |
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| 摘 要： | 灯盏花素是从菊科飞蓬属植物短亭飞蓬灯盏细辛中提取的黄酮活性成分,具有降低血液黏稠度,抑制血小板聚集,抗缺血及灌注损伤,清除氧自由基、抗氧化,抑制蛋白激酶C,改善脑微循环及器官血流动力学等多方面作用,在心脑血管疾病等领域应用广泛。笔者综述了近年来灯盏花素在急性脑梗死领域的药理、作用机制、临床应用等方面的最新研究进展。
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| 关 键 词： | 灯盏花素 急性脑梗死 心脑血管疾病 |
Mechanism of action and clinical application of breviscapine on treatment of acute cerebral infarction |
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| HE Miao,LI Minqing,WEN Xi’na LI Shujuan,WU Youqiong,XU Jianzong,GENG Jiabin. Mechanism of action and clinical application of breviscapine on treatment of acute cerebral infarction[J]. China Medicine and Pharmacy, 2012, 0(22): 30-31,54 |
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| Authors: | HE Miao LI Minqing WEN Xi’na LI Shujuan WU Youqiong XU Jianzong GENG Jiabin |
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| Affiliation: | Department of Traditional Chinese Med.,Dazhou Central Hospital,Dazhou 635000,China |
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| Abstract: | Breviscapine is one of the flavonoid active ingredient abstracted from Erigeron Breviscapus,which belongs to Erigeron breviscapus(vant) Hand Mass.Breviscapine has been widely used for treating heart-cerebrovascular diseases because of its abilities to reduce blood viscosity,inhibit platelet aggregation,resist injury of ischemia and reperfusion,scavenge oxygen free radicals,provide anti-oxidation protection,inhibit protein kinase C and improve hemodynamics of cerebral microcirculation and other organs.This paper reviews the recent advances of pharmacology,mechanism of action and clinical application of breviscapine on treatment of acute cerebral infarction. |
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| Keywords: | Breviscapine Acute cerebral infarction Heart-cerebrovascular diseases |
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