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| 姜黄素-钌配合物的合成和抗氧化活性研究 | |
| 引用本文： | 陈莉敏,林友文,康建军,邱彬.姜黄素-钌配合物的合成和抗氧化活性研究[J].海峡药学,2010,22(5):224-226. |
| 作者姓名： | 陈莉敏 林友文 康建军 邱彬 |
| 作者单位： | 1. 福州大学化学化工学院,福州,350002;福建医科大学药学院,福州,350004 2. 福建医科大学药学院,福州,350004 3. 福州大学化学化工学院,福州,350002 |
| 基金项目： | 福建省自然科学基金计划资助项目，福建省教育厅科技项目 |
| 摘 要： | 目的合成和表征了姜黄素-钌金属配合物,并对其抗氧化活性进行初步的研究。方法以姜黄素为配体合成其钌的配合物,用红外光谱、紫外光谱、元素分析对配合物进行了表征,并进行抗氧化活性初步筛选。结果合成了姜黄素-钌的金属配合物,并确定其结构。结论活性筛选结果表明,配合物对自由基清除活性好于姜黄素。 |
| 关 键 词： | 姜黄素 配合物 抗氧化 |
Synthesis and Anti-oxidation Activity of Curcumin-ruthenium (Ⅲ) Complexe |
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| CHEN Li-min,LIN You-wen,KANG Jiang-jun,CHEN Guo-nan.Synthesis and Anti-oxidation Activity of Curcumin-ruthenium (Ⅲ) Complexe[J].Strait Pharmaceutical Journal,2010,22(5):224-226. | |
| Authors: | CHEN Li-min LIN You-wen KANG Jiang-jun CHEN Guo-nan |
| Institution: | CHEN Li-min,LIN You-wen,KANG Jiang-jun,CHEN Guo-nan(1.College of Chemistry and Chemical Engineering,Fuzhou University,Fuzhou 350002,China;2.Faculty of Pharmacy,fujian medical university,fuzhou,350004,China) |
| Abstract: | OBJECTIVE To synthesize and characterize Curcumin-ruthenium（Ⅲ） Complexe,and study the Anti-oxidation Activity of the complexe.METHODS The title complexe was prepared by using curcumin as ligands.This complexe was characterized by IR spectra,UV spectra and elemental analyses and screened by anti-oxidation model.RESULTS Curcumin-ruthenium（Ⅲ） Complexe was synthesized and its structure was determined.CONCLUSION The Curcumin-ruthenium（Ⅲ） Complexe have better anti-oxidation activity than curcumin and are worthy of further study. |
| Keywords: | Curcumin Complex Anti-oxidation activity |
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