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| 正交试验法优选益气膏提取工艺研究 | |
| 引用本文： | 马月光,李进,徐世芳.正交试验法优选益气膏提取工艺研究[J].海峡药学,2009,21(2):16-17. |
| 作者姓名： | 马月光 李进 徐世芳 |
| 作者单位： | 1. 浙江省杭州市第一人民医院,杭州,310006 2. 浙江大学医学院附属第一医院杭州,310003 3. 浙江省医学科学院药物研究所,杭州,310013 |
| 摘 要： | 目的优化益气膏最佳提取工艺。方法采用正交试验法，以得膏率和芍药苷的含量为考核指标。对提取时间、提取次数、加水量等因素进行研究。结果最佳提取工艺为加10倍量水，提取3次，每次2h。结论该提取工艺合理。为工业化生产提供了科学依据。 |
| 关 键 词： | 益气膏 芍药苷 正交试验 高效液相色谱 |
Optimal extraction technology of Yiqi cream by orthogonal design |
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| MA Yue-guang,LI Jin,XU Shi-fang.Optimal extraction technology of Yiqi cream by orthogonal design[J].Strait Pharmaceutical Journal,2009,21(2):16-17. | |
| Authors: | MA Yue-guang LI Jin XU Shi-fang |
| Institution: | MA Yue-guang, LI Jin, XU Shi-fang( 1. First People＇ s Hospital of Hangzhou, Hangzhou 310006, China; 2. The First Affiliated Hospital of College of Medicine, Zhejiang University,Hangzhou 310003, China; 3.Institute of Medica Materia, Zhejiang Academy of Medicine, Hangzhou 310013, China) |
| Abstract: | OBJECTIVE To optimize the extraction process for Yiqi cream. METHOD An experiment based on the orthogonal test design was performed to study the impact of extraction time, extraction frequency, and amount of solvent on the extraction rate and content of paeoniflorin. RESULTS The optimal condition was added 10 times amount of water for three times and 2 hours for each time. CONCLUSION This extraction technique is reasonable and it provides a scientific basis for industrialized extraction process. |
| Keywords: | Yiqi cream Paeoniflorin Orthogonal test HPLC |
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