加味生化汤预防血瘀型产后恶露不绝对血液流变学的影响

目的观察加味生化汤预防血瘀型产妇产后恶露不绝对血液流变学的影响。方法将经阴道分娩的血瘀型产妇120例,完全随机分为观察组、对照组、空白组,每组各40例。观察组服用自拟加味生化汤,对照组予缩宫素10 U肌内注射,空白组服用安慰剂（多维元素胶囊）。观察3组患者中医证候的改变,产后恶露不绝的发生率以及治疗前后血液流变学指标的变化。结果观察组中医证候的总有效率为95.0%,对照组、空白组分别为75.0%、82.5%,观察组与其余两组比较,差异有统计学意义（P〈0.05）,对照组与空白组比较,差异无统计学意义（P〉0.05）;观察组、对照组、空白组产后恶露不绝的发生率分别为15.0%、32.5%、35.0%,观察组产后恶露不绝的发生率明显低于对照组、空白组（P〈0.05）,对照组与空白组比较,差异无统计学意义（P〉0.05）;观察组血液流变学各项指标与治疗前比较明显改善（P〈0.05）,与其余两组比较,差异有统计学意义（P〈0.05）。结论加味生化汤能有效预防血瘀型产妇产后恶露不绝的发生,能明显改善其血液流变学各项指标,值得临床推广。

Effect of supplemented Shenghua decoction on hemorheology in preventing postpartum persistent flow of lochia of blood stasis type

Objective To observe the effect of supplemented Shenghua decoction on hemorheology in preventing postpartum persistent flow of lochia of blood stasis type. Methods 120 maternals of blood stasis type with transvaginal delivery were completely random divided into the observation group and the control group and blank group（40 cases each group）.The observation group was given self-made supplemented Shenghua decoction,the control group was given oxytocin of 10 U by intramuscular injection,the blank group was treated with placebo（multivitamin capsule）.The change of TCM syndrome,the occurrence rate of postpartum persistent flow of lochia and the variation of hemorheology index before and after treatment of the three groups were compared. Results The total effective rate of TCM syndrome were 95.0% in the observation group,while it was 75.0% and 82.5% in the control group and the blank group,and there was a statistical difference of between the observation group and the other two group（P0.05）,there was no statistical difference between the control group and the blank group（P0.05）;the incidence rate of postpartum persistent flow of lochia of the observation group,the control group and the blank group were 15.0%,32.5%,35.0% respectively,the incidence rate of the postpartum persistent flow of lochia in the observation group was significantly lower than that in the control group and the blank group（P0.05）,and there was no statistical difference between the control group and the blank group（P0.05）;the hemorheology indexes in the observation group were significantly improved compared with before treatment（P0.05）,and there was a statistical difference of between the observation group and the other two group（P 0.05）. Conclusion Supplemented Shenghua decoction can effectively prevent postpartum persistent flow of lochia of blood stasis type woman and can significantly improve the hemorheology index.It is worthy of clinical popularization.