非酒精性脂肪肝与2型糖尿病冠心病危险因素临床分析

目的:2型糖尿病(T2DM)合并非酒精性脂肪肝病(NAFLD)患者的心血管疾病风险因素及其与心血管疾病的关系的分析。方法:对某院收治的T2DM 210例患者根据病史及肝脏B超检查结果分为NAFLD组和非NAFLD组,观察其体质指数(BMI)、血脂、糖化血红蛋白(HbA1c)情况及其与心血管病患病率的关系。结果:126例(60.00%)住院T2DM患者伴NAFLD,NAFLD组有较高的BMI、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)水平,与非NAFLD组比较,差异有统计学意义(P<0.05);NAFLD组心血管病患病率明显高于非NAFLD组,差异有统计学意义(P<0.05)。结论:2型糖尿病患者NAFLD发生率高,并且血脂代谢紊乱、HbA1c升高等心血管危险因素明显增加,NAFLD增加了2型糖尿病患者心血管病的风险。

Clinical Study of the Risk Factors of Cardiovascular Disease in Patients with Type Ⅱ Diabetic Combined with Nonalcoholic Fatty Liver Disease

Objective:To assess the risk factors of cardiovascular disease(CVD) and the relationship between nonalcoholic fatty liver disease(NAFLD) and CVD in patients with Type 2 diabetic combined with NAFLD.Methods:The 210 patients with Type 2 diabetic were divided into two groups(NAFLD-Group and non-NAFLD group)by liver ultrasonography,analysis BMI,blood fat,HbA1c and the relationship between NAFLD and CVD.Results: Among them,126 cases(60.00%) were complicated with NAFLD,NAFLD group had higher trig1ycerides(TG)and low density lipoprotein cho1estero1(LDL-C) levels than those without NAFLD(P<0.01),and had lower high density lipoprotein cho1estero1(HDL-C) levels than those without NAFLD(P<0.05).Moreover,the prevalent of CVD was also higher in NAFLD group.Conclusion: NAFLD is a common condition complicated with type Ⅱ diabetes.The risk factor of CVD,such as BMI,Lipid Metabolism,and HbA1c increased,and NAFLD increases the risk of CVD.