|
|||||
|
|
| 克林霉素的不良反应与用药安全性 | |
| 引用本文： | 黄祥,李军,郑丽娜,李勇.克林霉素的不良反应与用药安全性[J].药物不良反应杂志,2003,5(2):83-87. |
| 作者姓名： | 黄祥 李军 郑丽娜 李勇 |
| 作者单位： | 1. 北京军区总医院,北京,100700 2. 东莞市人民医院,广东,东莞,531000 3. 唐山市妇幼保健院,河北,唐山,063000 |
| 摘 要： | 探讨克林霉素的不良反应(ADR)及其用药安全性。方法:通过将248例ADR病例按WHO ADR器官/系统类型分类后,对其ADR临床表现、并用药物与ADR发生机制以及克林霉素的安全性进行分析探讨。结果:248例ADR病例症状涉及15个器官/系统类型,前三位是皮肤及其附件损害、胃肠系统损害及中枢和外周神经系统损害。结论:应重视克林霉素的合理用药,警惕临床应用中可能因本品的药物相互作用诱发严重ADR的潜在危害性。 |
| 关 键 词： | 克林霉素 严重不良反应 神经肌肉阻滞 用药安全性 |
Adverse reactions and safety of clindamycin |
|
| Huang Xiang,Li Jun,Zheng Lina,Li Yong.Adverse reactions and safety of clindamycin[J].Adverse Drug Reactions Journal,2003,5(2):83-87. | |
| Authors: | Huang Xiang Li Jun Zheng Lina Li Yong |
| Abstract: | To evaluate the side-effects induced by clindamycin and its safety in clinical practice. Method: According to organ/system types recommended by WHO, the adverse reactions of clindamycin in 248 cases were classified. Results; 15 organs/systems were involved and the commonest ADRs were damages of skin and its appendages, digestive system, central and peripheral nervous system. Conclusion; Clindamycin should be used with caution in patients with a history of hypersensitivity. There is a potential danger of significant diarrhoea, hematuria and respiratory depression mainly because of drug interactions. |
| Keywords: | clindamycin serious adverse drug reactions neuromuscular blockade drug safety |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |