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血必净联合甲强龙治疗百草枯中毒患者肺损伤的研究
引用本文:刘伟,赵敏.血必净联合甲强龙治疗百草枯中毒患者肺损伤的研究[J].实用药物与临床,2009,12(1).
作者姓名:刘伟  赵敏
作者单位:中国医科大学附属盛京医院急诊科,沈阳,110004
摘    要:目的评价血必净联合甲强龙治疗百草枯中毒患者肺损伤的临床疗效。方法选择我院急诊2004年1月-2008年9月收治的急性百草枯中毒患者51例,随机分为对照组(24例)与治疗组(27例)。对照组给予常规治疗。治疗组在对照组的基础上应用血必净注射液50mL,2次/d,连用7d;甲强龙500mg,1次/d,连用5d。结果治疗组发生低氧血症、Ⅰ型呼吸衰竭、ALI、ARDS、机械通气例数少于对照组,P<0.05;治疗组肺纹理增强、点片状影、磨玻璃影、胸腔积液、纤维条索、网状影、结节影表现明显少于对照组,P<0.05;治疗组入院后发生MODS、死亡数少于对照组,P<0.05。结论血必净联合大剂量甲强龙治疗可减轻肺组织损伤程度,降低患者死亡率。

关 键 词:血必净  甲强龙  百草枯中毒

Effect of Xuebijing combined with Methylprednisolone on paraquat poisoning with lung injury
LIU Wei,ZHAO Min.Effect of Xuebijing combined with Methylprednisolone on paraquat poisoning with lung injury[J].Practical Pharmacy and Clinical Remedies,2009,12(1).
Authors:LIU Wei  ZHAO Min
Institution:Department of Emergency;Shengjing Hospital of CMU;Shenyang 110004;China
Abstract:Objective To evaluate the therapeutic effect of Xuebijing combined with Methylprednisolone on Paraquat(PQ)poisoning with lung injury.Methods 51 patients with acute paraquat poisoning were divided into control group(24 cases)and treatment group(27 cases).Control group was given basic therapy.Treatment group received Xuebijing(50 mL,twice per day)and Methylprednisolone(500 mg,once per day)for 7 d and 5 d respectively,other treatments were the same as control group.Results Compare to the control group,the inci...
Keywords:Xuebijing  Methylprednisolone  Paraquat poisoning  
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