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食管鳞癌微血管密度与病理特征关系探讨
引用本文:陈奎生,魏新设,张云汉,高冬玲,张岚,宋一民.食管鳞癌微血管密度与病理特征关系探讨[J].医药论坛杂志,2005,26(20):10-11.
作者姓名:陈奎生  魏新设  张云汉  高冬玲  张岚  宋一民
作者单位:郑州大学第一附属医院病理科,郑州市,450052;河南省长葛市人民医院,461500
摘    要:目的 探讨食管鳞癌组织中微血管密度与食管癌临床病理特征之间的关系。方法 应用抗CD34抗体检测食管鳞癌组织中MVD。结果 不同大小肿瘤组间MVD比较无明显差异(P〉0.05);不同分化程度食管鳞癌MVD比较差异有显著性(P〈0.05);不同浸润深度食管鳞癌MVD比较差异有显著性(P〈0.05);有淋巴结转移组MVD与无淋巴结转移组比较差异有统计学意义(P〈0.05)。结论 MVD与食管鳞癌的分化程度、浸润深度及淋巴结转移有关。

关 键 词:食管癌  微血管密度  免疫组织化学
文章编号:1672-3422(2005)20-0010-02
收稿时间:2005-07-13
修稿时间:2005年7月13日

Relationship between MVD and Clinical Pathologic Features in Tissue of Esophageal Squamous Cell Carcinoma
CHEN Kuisheng, WEI Xinshe, ZHANG Yunhan,et al.Relationship between MVD and Clinical Pathologic Features in Tissue of Esophageal Squamous Cell Carcinoma[J].Journal of Medical Forum,2005,26(20):10-11.
Authors:CHEN Kuisheng  WEI Xinshe  ZHANG Yunhan  
Abstract:Objective To study the relationship between MVD and clinical pathologic features in tissues of esophageal squamous cell carcinoma .Methods MVD in esophageal carcinoma was examined by immunohistochemical S-P method with anti-CD34 antibody. Results There is no significant difference among the size of the tumor( P >0.05), MVD was significantly correlated with pathological grade, lymph node metastasis and infiltrative deepness ( P <0.05, P <0.05) . Conclusion MVD was significantly correlated with histology grade, invasion depth and lymph node metastasis of esophageal squamous cell carcinoma.
Keywords:Esophageal carcinoma  MVD  Immunohistochemistry
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