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VEGF MVD在子宫腺肌病中的表达
引用本文:王雪梅,王雪梅.VEGF MVD在子宫腺肌病中的表达[J].医药论坛杂志,2007,28(7):10-11.
作者姓名:王雪梅  王雪梅
作者单位:1. 焦作市第二人民医院妇产科,焦作市,454000
2. 郑州大学第三附属医院生殖医学中心,郑州市,450052
摘    要:目的 探讨子宫腺肌病异位内膜组织中血管内皮生长因子(VEGF)和微血管密度(MVD)的表达.方法 采用免疫组织化学方法检测子宫腺肌病异位内膜与正常子宫内膜中VEGF和MVD的表达.结果 子宫腺肌病异位内膜组织中VEGF和MVD在增生期和分泌期的表达均明显高于正常内膜(P<0.05).结论 异位内膜组织中VEGF和MVD的高表达可能对子宫腺肌病的发生发展起重要作用.

关 键 词:子宫腺肌病  血管内皮生长因子  微血管密度  VEGF  子宫腺肌病  表达  Microvascular  Density  Endothelial  Growth  Factor  Vascular  作用  发展  发生  正常子宫内膜  分泌期  增生期  结果  异位内膜组织  检测  免疫组织化学方法  微血管密度  血管内皮生长因子
文章编号:1672-3422(2007)07-0010-02
修稿时间:2007-02-26

Expression of Vascular Endothelial Growth Factor and Microvascular Density in Adenomyosis
WANG Xuemei,WANG Xuemei.Expression of Vascular Endothelial Growth Factor and Microvascular Density in Adenomyosis[J].Journal of Medical Forum,2007,28(7):10-11.
Authors:WANG Xuemei  WANG Xuemei
Abstract:Objective To investigate the expression of vascular endothelial growth factor(VEGF) and microvascular density(MVD) in ectopic endometrium from patients with adenomyosis.Methods Immunohistochemical method was used to determine the expression of VEGF and MVD in ectopic endometrium from patients with adenomyosis and the endometrium of controls.Results The expression of VEGF and MVD in entopic endometrium with adenomyosis was significantly higher(P<0.05)than that of normal endometrium.Conclusion The higher expression of VEGF AVD may be involved in the development of adenomyosis.
Keywords:Adenomyosis  Vascular endothelial growth factor  Microvascular density
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