| 紫杉醇联合奥沙利铂和卡培他滨治疗晚期胃癌 |
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| 引用本文： | 薛永飞.紫杉醇联合奥沙利铂和卡培他滨治疗晚期胃癌[J].医药论坛杂志,2011(17):88-89. |
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| 作者姓名： | 薛永飞 |
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| 作者单位： | 南阳市中心医院肿瘤内科; |
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| 摘 要： | 目的探讨紫杉醇联合奥沙利铂和卡培他滨治疗晚期胃癌的疗效和不良反应。方法选择南阳市中心医院2007年5月—2010年l2月收治的30例晚期胃癌患者,采用紫杉醇联合奥沙利铂和卡培他滨方案治疗:紫杉醇75mg/m2,第1、8d,静脉滴注;奥沙利铂130mg/m2,第1d,静脉滴注;卡培他滨800mg/m2第1～14d,分两次口服,21d为1周期。两个周期评价疗效。结果全组30例均可评价疗效,其中PR 14例,SD 8例,PD 8例,客观有效率为73.3%;中位肿瘤进展时间为6.1个月,中位总生存期为10.5个月。不良反应主要为骨髓抑制、恶心呕吐和外周神经毒性。结论紫杉醇联合奥沙利铂和卡培他滨治疗晚期胃癌疗效较好,不良反应可耐受,值得临床进一步研究。
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| 关 键 词： | 晚期胃癌 紫杉醇 奥沙利铂 卡培他滨 化学治疗 |
Paclitaxel combined with oxaliplatin and capecitabine in treatment of advanced gastric cancer |
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| XUE Yong-fei Nanyang Central Hospital,Nanyang,Henan ,China.Paclitaxel combined with oxaliplatin and capecitabine in treatment of advanced gastric cancer[J].Journal of Medical Forum,2011(17):88-89. |
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| Authors: | XUE Yong-fei Nanyang Central Hospital Nanyang Henan China |
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| Institution: | XUE Yong-fei Nanyang Central Hospital,Nanyang,Henan 473000,China |
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| Abstract: | Objective To investigate the efficacy and adverse reactions of paclitaxel and oxaliplatin and capecitabine in treatment of advanced gastric cancer. Methods A hospital in May 2007 to Dec 2010 admitted 30 patients with advanced gastric cancer with paclitaxel and oxaliplatin and capecitabine regimen: paclitaxel 75mg/m2,days 1,8,intravenous drip note;Oxaliplatin 130mg/m2,day 1,intravenous infusion;Capecitabine 800mg/m2 1 to 14 days,two oral,21 days cycle.Two cycles were evaluated. Results Totally 30 patients ca... |
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| Keywords: | Advanced gastric cancer Paclitaxel Oxaliplatin Capecitabine Chemotherapy |
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