青岛市城阳区非酒精性脂肪肝患病率及危险因素分析

目的了解健康人群中非酒精性脂肪肝病(NAFLD)患病率及相关危险因素,为防治NAFLD提供依据。方法以城阳人民医院健康体检的745例人群为研究对象,以是否患NAFLD将其分为NAFLD组和对照组,收集相关资料进行显著性分析。结果 NAFLD总检出率23.0%,有明显的家族史、性别、年龄差异;NAFLD组各危险因素检出率均高于对照组;除HDL,NAFLD组各临床指标均值均高于对照组;Logistic回归分析显示家族史、年龄、BMI、SBP、TG、UA、FINS、CHD、HT、HDL与NAFLD的发生密切相关。结论家族史、肥胖、年龄、高血压、TG、UA、FINS、CHD、HT升高是NAFLD的危险因素,HDL是其保护因素。

Analysis of the prevalence rate of nonalcoholic fatty liver disease and its risk factors in Chengyang

Objective To investigate the prevalence rate of nonalcoholic fatty liver disease and its risk factors among the people taken health examination and provide scientific basis for prevention and treatment.Methods The medical examination results of 745 cases were collected for statistical analysis from Chengyang People’s Hospital.Results The total incidence of nonalcoholic fatty liver disease was 23.0%.There was significant difference between family history,gender groups and among age groups.The incidence rate of NAFLD was varied from different occupations and the risk factors for NAFLD group had higher detection rate.All clinical indicators of NAFLD group were higher than that of control except high-density lipoprotein.Multiple logistic regression analysis revealed that the risk factors of NAFLD including family history,AGE,BMI,SBP,TG,UA,FINS,CHD,HT and HDL were highly relative to NALFD.Conclusion The risk factors for NAFLD are family history,obesity,age,hypertension,TG,UA,FINS,CHD,HT.HDL is the protective factor for NALFD.